Results 191 to 200 of about 31,883 (222)

Endoglin (CD105): A Target for Anti-angiogenetic Cancer Therapy

Current Drug Targets, 2003
Targeting of tumor vasculature is a promising strategy for cancer treatment. Among endothelial cell markers, Endoglin, a cell membrane glycoprotein, is emerging as an attractive therapeutic target on angiogenetic blood vessels, and it currently represents a powerful marker to quantify tumor angiogenesis.
Fonsatti E, Altomonte M, Arslan P, Maio M   +3 more
openaire   +3 more sources

The prognostic value of endoglin (CD105) expression in ovarian carcinoma

International Journal of Gynecological Cancer, 2006
Intratumoral angiogenesis has become an important issue after the identification of antiangiogenic therapeutics. The purpose of this study was to investigate the prognostic value of CD105 in patients with ovarian cancer and also to compare with CD31. Fifty-eight patients were included to this study.
VURAL, ÇİĞDEM, Erdem, MEHMET, Guner, H., Ataoglu, O., Acar, A., Arisoy, O., Onan, A., Erdem, O., Taskiran, C.   +8 more
openaire   +3 more sources

Endoglin (CD105) expression in human renal cell carcinoma

BJU International, 2006
OBJECTIVE To evaluate the prognostic potential of endoglin (CD105) expression in human renal cell carcinoma (RCC), as endoglin is a cell membrane glycoprotein expressed in tumour‐associated vascular endothelium and a marker of angiogenesis; intratumoral microvessel density assessed by endoglin staining has ...
Johanna, Sandlund, Ylva, Hedberg, Anders, Bergh, Kjell, Grankvist, Börje, Ljungberg, Torgny, Rasmuson   +5 more
openaire   +2 more sources

Abstract B237: CD105: A therapeutic target for sarcomas.

Molecular Cancer Therapeutics, 2013
Abstract Purpose: Endoglin/CD105 is a homodimeric transmembrane glycoprotein that is expressed on the proliferating endothelium of solid tumors. TRC105, the chimeric IgG1 antibody with high affinity binding for human CD105, has recently undergone human testing.
Karen Fritchie, Steven Attia, Scott Okuno, Carola Arndt, Steven Robinson   +4 more
openaire   +1 more source

Effects of CD105 Nb68 on Biological Behaviors of CD105 Positive Tumor Cells

Journal of Contemporary Medical Practice, 2022
openaire   +1 more source

Tumor Angiogenesis in Cancers: Expression of CD105 Marker

2009
Angiogenesis is an important step in the process of cancer growth and wound healing (Folkman 1971). Cancer is always accompanied by angiogenesis. Angiogenesis is a complex of endothelial cell growth through an interaction of growth factors and their ligands and of sustaining matrices.
Osamu Tokunaga, Rahmawati Minhajat, Daisuke Mori   +2 more
openaire   +1 more source

EDITORIAL. CD105 AND ANGIOGENESIS

The Journal of Pathology, 1996
P. KUMAR, J. M. WANG, C. BERNABEAU
openaire   +1 more source

CD105

1997
A. Neil Barclay, Marion H. Brown, S.K. Alex Law, Andrew J. McKnight, Michael G. Tomlinson, P. Anton van der Merwe   +5 more
openaire   +1 more source

CD105 in the Progression and Therapy of Colon Cell Carcinoma

Colon cell carcinoma (CRC) poses a significant global health challenge, demanding thorough exploration. This chapter meticulously navigates the multifaceted landscape of CRC, elucidating its definition, prevalence, and established risk factors. The spotlight then shifts to CD105, an enigmatic glycoprotein intricately woven into the fabric of CRC ...
openaire   +1 more source

Expression Of (CD105) And ( VEGF-R3) In Dermoidcyst

International Journal of Pharmaceutical Research, 2020
openaire   +1 more source