Results 121 to 130 of about 17,756 (247)

COMIP‐002: 27‐color flow cytometry for measurable residual disease detection in B‐cell lymphoblastic leukemia

Cytometry Part B: Clinical Cytometry, Volume 110, Issue 5, Page 321-325, September 2026.
Ryan C. Shean, Patricia Davis, Jeffery Jacobsen, David P. Ng   +3 more
wiley   +1 more source

Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor

, 2013
Current therapeutic regimens for acute myeloid leukaemia (AML) are still associated with high rates of relapse. Immunotherapy with T-cells genetically modified to express chimeric antigen receptors (CARs) represents an innovative approach.
Bonnet, D., Lopez, A., Tettamanti, S., Marin, V., Biagi, E., Magnani, C., Cribioli, E., Galimberti, S., Pizzitola, I., Giordano Attianese, G., Maltese, F., Biondi, A.   +11 more
core   +1 more source

Abstract 597: Bispecific anti-CD123 x anti-CD3 ADAPTIR™ molecules for redirected T-cell cytotoxicity in hematological malignancies

, 2017
Introduction: CD123 is a component of the IL-3 receptor expressed in several hematological malignancies including AML, ALL, HCL, and MDS. CD123 is a compelling target in AML due to its overexpression on AML blasts as well as leukemic stem cells, which ...
Rebecca Gottschalk, Megan Aguilar, Gary Li, David Bienvenue, Hang Fang, Robert Bader, Catherine McMahan, Jeannette Bannink, Brian Woodruff, Mollie Daugherty, Robert E. Miller, Gabriela H. Hoyos, Michael R. Comeau, Starrla Johnson, John W. Blankenship, Lara Parr, Danielle Mitchell, Nicole Zhang, Peter Pavlik, Maria Dasovich, Lynda Misher, Toddy Sewell, Jane A. Gross   +22 more
core   +1 more source

CD123 monoclonal antibody in myelodysplastic syndrome

Hematology/Oncology and Stem Cell Therapy, 2011
De Salvo, Luigi, Salas, Rodolfo, De Salvo, Dalila, Medina, Weir Jesús, Nunez, Anamaria, Plumacher, Zaida, Fernandez, Olga, Acosta, Mariela, Duerto, Mirian, Paz, Luis, Salas, Dalida, Fuenmayor, Alba   +11 more
openaire   +2 more sources

Production and testing of CD123 specific CAR⁺ T cells with CD28 vs. CD137 costimulatory domains.

, 2016
(A) CAR expression in CD123-CD28 (middle) and CD123-CD137 (right) CAR+ and CARneg T cells (left) on day 1and day 35 after electroporation and co-culture on AaPC, Clone 1-CD123.
Tiejuan Mi (332266), Sourindra Maiti (384485), Tamara Laskowski (3070806), Laurence J. N. Cooper (187481), Helen Huls (384486), Richard E. Champlin (187480), Simon Olivares (417497), Harjeet Singh (187475), Drew Deniger (3070812), George McNamara (3070809), Hiroki Torikai (127874), Radhika Thokala (747629)   +11 more
core   +1 more source

Control effect of Dasatinib on the treatment of acute myeloid leukemia and adverse events of CD123 targeting CAR-T: a case report and literature review

陆军军医大学学报
Objective To preliminarily explore the efficacy of chimeric antigen receptor T cells (CAR-T) targeting CD123 in the treatment of acute myeloid leukemia (AML) and the role of dasatinib in the treatment of CD123 targeting CAR-T induced side effects ...
LI Chunmin, LI Chunmin, LI Yu, YUAN Zhongtao   +3 more
doaj   +1 more source

Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia

, 2019
Monoclonal antibodies are being considered as biopharmaceuticals for the in vivo targeting of acute myeloid leukemia. Here we describe the generation and characterization of a fully-human monoclonal antibody specific to CD123, a surface marker which is ...
Manz, Markus G, Murer, Patrizia, Rinaldi, Francesco, Hutmacher, Cornelia, Volta, Laura, Myburgh, Renier, Neri, Dario   +6 more
core   +1 more source

Proof-of-concept for Rapidly Switchable Universal CAR-T Platform with UniCAR-T-CD123 in Relapsed/Refractory AML.

Blood, 2021
M. Wermke, S. Kraus, A. Ehninger, R. Bargou, M. Goebeler, J. Middeke, C. Kreissig, M. von Bonin, J. Koedam, Michael Pehl, M. Bornhäuser, H. Einsele, G. Ehninger, M. Cartellieri   +13 more
semanticscholar   +1 more source

Supplementary Figures for: Preferential CD123 expression in granuloma annulare compared to necrobiosis lipoidica and sarcoidosis

This dataset contains Mendeley Supplementary Figures 1 through 6 for the Brief Report manuscript titled “Preferential CD123 expression in granuloma annulare compared to necrobiosis lipoidica and sarcoidosis.” Supplementary Figures 1 and 2 show CD123 ...
Hwang, Jonathan
core   +1 more source

Immunotherapies Targeting CD123 and CD303: A New Frontier in Treating Blastic Plasmacytoid Dendritic Cell Neoplasm

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy characterized by the overexpression of CD123 and CD303 surface antigens.
Sara Mele, Antonio Pinto, Domenico Galati, Fabrizia Florio, Rosaria De Filippi, Serena Zanotta   +5 more
core   +1 more source