Results 91 to 100 of about 15,811 (198)

Cargo Stability of Extracellular Vesicles Derived From Non‐Diseased Sources: Effects of Storage and Handling Conditions

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi, Mina Mohammadinasr, Roza Motavalli, Narges Arianfar, Attabak Toofani‐Milani, Moein Shirzad, Vahid Hosseini, Masoud Darabi   +7 more
wiley   +1 more source

Exploring the role of CD13 and inflammatory factors in radiation enteritis: insights from high-throughput proteomics and Mendelian randomization analysis

Discover Oncology
Background Radiation enteritis (RE) is an unavoidable complication during radiotherapy for pelvic malignancies, characterized by chronic inflammation, fibrosis, and vascular injury in the intestinal tissue.
Xue Ren, Feng Shang, Defu Yang, Ying Xu, Ying Yan   +4 more
doaj   +1 more source

An in vitro model of polycystic liver disease using genome-edited human inducible pluripotent stem cells

Stem Cell Research, 2018
In the developing liver, bile duct structure is formed through differentiation of hepatic progenitor cells (HPC) into cholangiocytes. A subtype of polycystic liver diseases characterized by uncontrolled expansion of bile ductal cells is caused by genetic
Akihide Kamiya, Hiromi Chikada, Kinuyo Ida, Emi Ando, Kota Tsuruya, Tatehiro Kagawa, Yutaka Inagaki   +6 more
doaj   +1 more source

Acute Myeloid Leukemia With KAT6A::CREBBP Rearrangement: A Rare Entity With Potential Diagnostic Pitfalls

International Journal of Laboratory Hematology, EarlyView.
Adam Lyle, Madhu P. Menon, Margaret C. Williams   +2 more
wiley   +1 more source

Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano, Miguel Maldonado, María‐José Camarasa, Sonia de Castro   +3 more
wiley   +1 more source

The pro-inflammatory cytokine 14-3-3 epsilon is a ligand of CD13 in cartilage

, 2015
International audienceOsteoarthritis is a whole-joint disease characterized by the progressive destruction of articular cartilage involving abnormal communication between subchondral bone and cartilage.
Sudre, Laure, Nefla, Meriam, Priam, Sabrina, Berenbaum, Francis, Denat, Guillaume, André-Leroux, Gwenaëlle, Jacques, Claire   +6 more
core   +1 more source

Virtual high-throughput screening: Potential inhibitors targeting aminopeptidase N (CD13) and PIKfyve for SARS-CoV-2

Open Life Sciences, 2023
Ruan Zijing, Tang Jiaxi, Zeng Mingtang, Fan Ping   +3 more
doaj   +1 more source

Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer

BMC Cancer, 2008
Background Radiotherapy can be used to treat all stages of cervical cancer. For improving local control via radiotherapy, it is important to use additional antitumor agents.
Nawa Akihiro, Terauchi Mikio, Kajiyama Hiroaki, Shibata Kiyosumi, Tsukamoto Hirohisa, Kikkawa Fumitaka   +5 more
doaj   +1 more source

Absence of CD13 Attenuates Acute Allograft Rejection

, 2016
The goal of transplantation is to implant healthy tissues or organs to successfully replace those that are damaged or defective. Currently allo-transplantation is almost universally prevented by immune mediated rejection without significant ...
Denninger, Jiyeon Kim
core   +1 more source

CD13 Destabilizes Vasculature in Tumors

, 2013
Optimal tumor growth relies on the integration of inflammation and angiogenesis such that a number of molecules are critical regulators of both processes contributing to the overall orchestration of cancer growth and progression.
Vernier, Kaitlyn M
core   +1 more source