Results 51 to 60 of about 33,329 (197)

Enhancing the Oncolytic Activity of CD133-Targeted Measles Virus: Receptor Extension or Chimerism with Vesicular Stomatitis Virus Are Most Effective

open access: yesFrontiers in Oncology, 2017
Therapy resistance and tumor recurrence are often linked to a small refractory and highly tumorigenic subpopulation of neoplastic cells, known as cancer stem cells (CSCs). A putative marker of CSCs is CD133 (prominin-1).
Dina Kleinlützum   +12 more
doaj   +1 more source

Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by 89Zr Immuno-PET

open access: yesMolecular Imaging, 2022
We developed an immuno-PET technique that monitors modulation of tumor CD133 expression, which is required for the success of CD133-targeted therapies. Methods. Anti-CD133 antibodies were subjected to sulfhydryl moiety-specific 89Zr conjugation.
Kyung-Ho Jung   +5 more
doaj   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

open access: yesAdvanced Science, EarlyView.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang   +3 more
wiley   +1 more source

Isolation and Identification of CD133 Positive and Negative Cells from Human Lung Cancer and Screening of the Differential Genes between the Positive and Negative Cells

open access: yesChinese Journal of Lung Cancer, 2015
Background and objective It has been proven that cancer stem cell existed in variety of cancer, which an significant difference of biological characteristics was observed between the cancer stem cells and non-cancer stem cells. And CD133 is considered to
Shaoqiu ZHENG   +4 more
doaj   +1 more source

CD133 antigen expression in ovarian cancer [PDF]

open access: yesBMC Cancer, 2009
Much attention has been recently focused on the role of cancer stem cells (CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to proliferate and self-renew extensively, thus sustaining tumor growth, the identification of CSCs through their antigenic profile might have relevant clinical implications.
Ferrandina G.   +6 more
openaire   +3 more sources

Study of XAV-939 effect on cancer stem cells of human colorectal cancer in heterotopic models in vivo

open access: yesЯкутский медицинский журнал
The purpose of this study was to investigate the numbers of cells with CSC markers in samples of human colorectal cancer (CRC) xenografts isolated in animals with tumors after exposure to the small molecule XAV-939, 5-fluorouracil, and to the combination ...
A. S. Goncharova   +6 more
doaj   +1 more source

All-trans retinoic acid suppresses malignant characteristics of CD133-positive thyroid cancer stem cells and induces apoptosis. [PDF]

open access: yesPLoS ONE, 2017
Recently, diagnoses of radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) have become more common; prognosis is poor. It has been suggested that cancer stem cells account for radiotherapy resistance.
Dan Mei   +6 more
doaj   +1 more source

Characteristics of CD133 Human Colon Cancer SW620 Cells

open access: yesCell Transplantation, 2010
Worldwide, colorectal cancer is the third most common type of cancer affecting both sexes. It has been proposed that a small subset of cancer cells (cancer stem cells) within each tumor is able to initiate tumor growth.
Hironobu Kawamoto M.D., Ph.D.   +13 more
doaj   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Isolation and characteristics of CD133−/A2B5+ and CD133−/A2B5− cells from the SHG139s cell line

open access: yesMolecular Medicine Reports, 2015
In glioma tissues, there are small cell populations with the capability of sustaining tumor formation. These cells are referred to as glioma stem cells (GSCs). However, the presence of subpopulations of GSCs, and the differences between each subpopulation remain to be fully elucidated.
HAN, YONG   +8 more
openaire   +3 more sources

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