Results 171 to 180 of about 7,732 (197)
A comprehensive analysis of immune checkpoint receptor-ligand pairs in aortic diseases highlights the immunosuppressive roles of CD155 and CD274. [PDF]
Shao Y +9 more
europepmc +1 more source
The role of immune checkpoints in modulating cancer stem cells anti-tumor immune responses: implications and perspectives in cancer therapy. [PDF]
Hussein OJ +9 more
europepmc +1 more source
The co-inhibitory receptor TIGIT promotes tissue-protective functions in T cells. [PDF]
Panetti C +16 more
europepmc +1 more source
NK cells in HPV-related tumorigenesis: mechanisms and clinical applications. [PDF]
Deng J +6 more
europepmc +1 more source
Increased Soluble CD155 in the Serum of Cancer Patients
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CD155: A Key Receptor Playing Diversified Roles
Current Molecular Medicine, 2022: Cluster of differentiation (CD155), formerly identified as poliovirus receptor (PVR) and later as immunoglobulin molecule, is involved in cell adhesion, proliferation, invasion and migration. It is a surface protein expressed mostly on normal and transformed malignant cells. The expression of the receptor varies based on the origin of tissue.
Shyam Sundar, Nandi +5 more
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CD155 in tumor progression and targeted therapy
Cancer Letters, 2022CD155, also known as the poliovirus receptor (PVR), has received considerable attention in recent years because of its intrinsic and extrinsic roles in tumor progression. Although barely expressed in host cells, CD155 is upregulated in tumor-infiltrating myeloid cells.
Zhan, Meixiao +6 more
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CD155 is a putative therapeutic target in medulloblastoma
Clinical and Translational Oncology, 2022Medulloblastoma is the most common pediatric malignant brain tumor, consisting of four molecular subgroups (WNT, SHH, Group 3, Group 4) and 12 subtypes. Expression of the cell surface poliovirus receptor (PVR), CD155, is necessary for entry of the viral immunotherapeutic agent, PVSRIPO, a polio:rhinovirus chimera.
Sean Li +12 more
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Tumor intrinsic and extrinsic immune functions of CD155
Seminars in Cancer Biology, 2020CD155 (PVR/necl5/Tage4), a member of the nectin-like family of adhesion molecules, is highly upregulated on tumor cells across multiple cancer types and has been associated with worse patient outcomes. In addition to well described cell-intrinsic roles promoting tumor progression and metastasis, CD155 has now been implicated in immune regulation.
O'Donnell, Jake. S. +3 more
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