Results 181 to 190 of about 7,732 (197)

Identification of secreted CD155 isoforms

Biochemical and Biophysical Research Communications, 2003
The CD155 gene is a member of the immunoglobulin superfamily. We first demonstrate the existence of soluble CD155 (sCD155) isoforms in culture medium conditioned by CD155-expressing cells, in human serum and in cerebrospinal fluid. sCD155 concentration was measured in human serum and cerebrospinal fluid using a specific ELISA.
Béatrice, Baury, Damien, Masson, Brian M, McDermott, Anne, Jarry, Hervé M, Blottière, Philippe, Blanchardie, Christian L, Laboisse, Patrick, Lustenberger, Vincent R, Racaniello, Marc G, Denis   +9 more
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Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo

Microbial Pathogenesis, 2000
Despite identification of the poliovirus (PV) receptor (CD155), mechanisms by which this molecule mediates paralytic disease remain obscure. Unanswered questions include CD155 localization in human tissues, the nature of cells supporting the first round of replication, identity of nonneural replication sites, and route of entry into the CNS. In earlier
M S, Freistadt, K E, Eberle
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PVR/CD155 Ala67Thr Mutation and Cleft Lip/Palate

Journal of Craniofacial Surgery, 2018
Abstract The 19q13 locus has been linked to cleft lip and palate by our group and independently by others. Here we fine mapped the region in an attempt to identify an etiological variant that can explain cleft lip and palate occurrence. A total of 2739 individuals born with cleft lip and palate, related to individuals born with
Alexandre R, Vieira, Ariadne, Letra, Renato M, Silva, Jose M, Granjeiro, Takehiko, Shimizu, Fernando A, Poletta, Juan C, Mereb, Eduardo E, Castilla, Iêda M, Orioli   +8 more
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CD155 and its receptors in cancer immune escape and immunotherapy

Cancer Letters, 2023
In recent years, there have been multiple breakthroughs in cancer immunotherapy, with immune checkpoint inhibitors becoming the most promising treatment strategy. However, available drugs are not always effective. As an emerging immune checkpoint molecule, CD155 has become an important target for immunotherapy.
Ruijia Zhou, Shiyin Chen, Qiwen Wu, Lingyun Liu, Yian Wang, Yongzhen Mo, Zhaoyang Zeng, Xuyu Zu, Wei Xiong, Fuyan Wang   +9 more
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CD155/TIGIT, a novel immune checkpoint in human cancers (Review)

Oncology Reports, 2021
CD155/T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a novel type of immune checkpoint. CD155 is an adhesion molecule that is upregulated during tumor progression and promotes the proliferative and migratory abilities of tumor cells via various pathways.
Lu, Liu, Xuewu, You, Sai, Han, Yu, Sun, Junhua, Zhang, Youzhong, Zhang   +5 more
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Physical association between CD155 and CD44 in human monocytes

Molecular Immunology, 1997
Regulation of CD44-mediated binding to hyaluronan is critical in normal and diseased immune cell function. In earlier work by others (Shepley and Racaniello, J. Virol., 68, 1301 1309), anti-CD44 mAb blocked poliovirus binding to CD155 (the poliovirus receptor) in HeLa cells, suggesting that CD155 and CD44 may be physically associated.
M S, Freistadt, K E, Eberle
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CD155 Expression in Early-Stage Lung Adenocarcinoma

The Annals of Thoracic Surgery
Cluster of differentiation (CD) 155 is a transmembrane protein that belongs to the nectin-like molecule family, which is widely overexpressed in several types of cancer. However, the clinical significance of CD155 in pathologic stage I lung adenocarcinoma remains poorly understood.We analyzed 320 patients diagnosed with pathologic stage I lung ...
Kyoto, Matsudo, Kazuki, Takada, Fumihiko, Kinoshita, Asato, Hashinokuchi, Taichi, Nagano, Takaki, Akamine, Mikihiro, Kohno, Tomoyoshi, Takenaka, Mototsugu, Shimokawa, Yoshinao, Oda, Tomoharu, Yoshizumi   +10 more
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CD155 as an emerging target in tumor immunotherapy

International Immunopharmacology
CD155 is an immunoglobulin-like protein overexpressed in almost all the tumor cells, which not only promotes proliferation, adhesion, invasion, and migration of tumor cells, but also regulates immune responses by interacting with TIGIT, CD226 or CD96 receptors expressed on several immune cells, thereby modulating the functionality of these cellular ...
Jiang-Wan Wu, Ying Liu, Xing-Jie Dai, Hong-Min Liu, Yi-Chao Zheng, Hui-Min Liu   +5 more
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TRANSLATIONAL OPPORTUNITIES FOR ANTIBODIES TARGETING PVR (CD155)

2022
Poliovirus receptor (PVR/CD155), expressed by many types of cancer cells, has been gaining considerable scientific interest because of its intrinsic and extrinsic roles in tumor progression. The intrinsic functions of PVR in tumor cells promote tumor progression and metastasis, whereas its extrinsic functions involve interaction with immune cell ...
Hiršl, Lea, Lenac Roviš, Tihana, Mazor, Marija   +2 more
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Expression and possible role of PVR/CD155/Necl-5 in osteoclastogenesis

Molecular and Cellular Biochemistry, 2007
Osteoclasts, the bone-resorbing cells, are differentiated from hematopoietic precursors via two-step cell-cell interactions. One is the interaction between the osteoclast precursor and the stromal cell to initiate differentiation. The other is the interaction among osteoclast precursors to form multinucleated osteoclasts.
Saori, Kakehi, Ken-ichi, Nakahama, Ikuo, Morita   +2 more
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