Results 231 to 240 of about 175,178 (288)

Secondary Chronic Myeloid Leukemia in the Blast Phase With Mixed Phenotype After Radiation Therapy: A Case Report. [PDF]

EJHaem
Aoki M, Maeda T, Kinoshita H, Taji Y, Shintani D, Takahashi N, Ebihara Y.   +6 more
europepmc   +1 more source

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source

Heterogeneous Activated B Cell Compartments Arising Early and Transiently After SARS-CoV-2 Vaccination. [PDF]

Eur J Immunol
Fernandez Blanco L, Kuijper LH, Kummer LYL, Verstegen NJM, Bos A, Claireaux M, Duurland MC, Jorritsma T, Steenhuis M, Kerster G, Vallejo JJG, van Gils MJ, van Dam KPJ, Stalman EW, Wieske L, Boekel L, Wolbink GJ, Tas SW, Rispens T, Kuijpers TW, Eftimov F, Brinke AT, van Ham SM, of T2B! Immunity Against SARS‐CoV‐2 Study Group.   +23 more
europepmc   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

T-cell-targeted fusogenic nanovesicles generate CAR-T cells in vivo for rheumatoid arthritis therapy. [PDF]

Biomark Res
Liang S, Lin K, Zhou S, Zeng Y, Chen Y, Sun Y, Xiao Z, Zhao G, Xu C, Lai P.   +9 more
europepmc   +1 more source

Colonic spatial single-cell proteomics and murine models link mitochondrial dysfunction to dimeric IgA-secreting plasma cell deficiency in Crohn's disease. [PDF]

Nat Commun
Raschdorf A, de Almeida LN, Solbach P, Kirstein MM, Marquardt JU, Schmelter F, Günther UL, Schlichting H, Hicken M, Christiansen L, Wiestler M, Tews HC, Bettenworth D, OUTLIVE-CRC consortium, Peipp M, Valerius T, Ragab M, Sauer T, Gemoll T, Ehlers M, Rosenstiel P, Manz RA, Künstner A, Busch H, Sina C, Derer S.   +25 more
europepmc   +1 more source

Circulating tumour cells (CTCs) in haematological malignancies: Advances in biology and clinical relevance with a focus on multiple myeloma

British Journal of Haematology, EarlyView.
Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu, Jui‐Feng Hsu, Jee‐Fu Huang, Yi‐Chang Liu   +3 more
wiley   +1 more source

Effects of anti-CD19 CAR-T cells in a murine model of IgG4-related disease. [PDF]

Arthritis Res Ther
Hu J, Yu Y, Yang Y, Feng Y, Zhuang A, Jia R, Song X.   +6 more
europepmc   +1 more source

Precision immunotherapy with CAR-T cells in pediatric B-cell acute lymphoblastic leukemia: advances and unanswered challenges. [PDF]

Front Oncol
Li F, Zheng L.
europepmc   +1 more source