Results 251 to 260 of about 175,178 (288)

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

Cell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo, Zexin Yang, Junsen She, Chen Fang, Yizhi Hu, Hefeng Huang, Ling Gao   +6 more
wiley   +1 more source

Biodegradable targeted polymeric mRNA nanoparticles enable in vivo CD19 CAR T cell generation and lead to B cell depletion. [PDF]

Sci Adv
Jain M, Est-Witte SE, Shannon SR, Neshat SY, Yu X, Dunham S, Tian T, Cheng L, Harris J, Konig MF, Tzeng SY, Schneck JP, Green JJ.   +12 more
europepmc   +1 more source

Fcγ-receptor-activation by circulating immune complexes in systemic autoimmune diseases and its reduction by CD19-CAR T cell therapy. [PDF]

Rheumatology (Oxford)
Freitag M, Kolb P, Falcone V, Claus M, Schröder P, Andreeva I, Rodon L, Ewald M, Deicher FS, Stütz AN, Distler JHW, Blank N, Grieshaber-Bouyer R, Muñoz LE, Lorenz HM, Schett G, Merkt W.   +16 more
europepmc   +1 more source

Immune‐related toxicity profile after haematopoietic stem cell transplantation in patients with B‐ALL given combination immunotherapy with rituximab, inotuzumab and blinatumomab

British Journal of Haematology, EarlyView.
Olayinka Okeleji, David McCall, Branko Cuglievan, Amber Gibson, Demetrios Petropoulos, Priti Tewari, Jeremy Connors, Irtiza N. Sheikh   +7 more
wiley   +1 more source

CISH, a key intracellular checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints. [PDF]

Commun Biol
Cano F, Bravo-Blas A, Colombe M, Cerrato C, Venigalla RKC, Preham O, Burns E, Mortimer P, Choudhry A, Slipek N, Johnson MJ, Webber BR, Moriarity BS, Lou E, Choudhry M, Klebanoff CA, Henley T.   +16 more
europepmc   +1 more source

Predictive value of MRD monitoring by BCR clonality in the ZUMA‐7 randomized clinical trial for CAR T therapy in r/r lymphoma

British Journal of Haematology, EarlyView.
Brodie Miles, Daqin Mao, Saran Vardhanabhuti, Davide Bedognetti, Simone Filosto, Rhine Shen   +5 more
wiley   +1 more source

Dysregulated Tfh/B cells and their interactions in neuromyelitis optica spectrum disorder. [PDF]

Front Immunol
Wang L, Zhou L, Wang Z, ZhangBao J, Huang W, Tan H, Fan Y, Lu C, Yu J, Wang M, Lu J, Zhao C, Wang J, Quan C.   +13 more
europepmc   +1 more source

The race between 4-1BB- and CD28-based CD19 CAR-T products in the therapy of B-cell malignancies.

Biochim Biophys Acta Rev Cancer
Krawczyk M, Drużyńska M, Bednarska E, Winiarska M.   +3 more
europepmc   +1 more source