Results 141 to 150 of about 126,758 (293)

Impact of measurable residual disease in combination with CD19 on postremission therapy choices for adult t(8;21) acute myeloid leukemia in first complete remission

open access: yesCancer Medicine
Background The post‐remission therapy (PRT) choices for adult t(8;21) acute myeloid leukemia (AML) in first complete remission (CR1) need to be further explored.
Xi Jia   +12 more
doaj   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Blinatumomab bridges the gap between leukemia and immunity

open access: yesOncoImmunology, 2017
Takahiro Yamazaki, Lorenzo Galluzzi
doaj   +1 more source

CD19: a promising target for systemic sclerosis

open access: yesFrontiers in Immunology
Systemic sclerosis (SSc) is an autoimmune disease characterized by immune dysregulation, vascular damage, and fibrosis. B cells play a significant role in SSc through autoantibody production, cytokine secretion, and T cell regulation. Autoantibodies like anti-topoisomerase I and anti-RNA polymerase III are specific to SSc and linked to clinical ...
openaire   +3 more sources

DinoFlow: Self‐supervised pretraining in flow cytometry enables accurate detection of common hematopathological disorders

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Flow cytometry is an essential component of routine hematological lab testing. Many computational methods have been proposed for the analysis of flow cytometry data, but most have focused on supervised learning for just one or a few specific disorders.
Brendan O'Fallon   +4 more
wiley   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

open access: yesBarrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu   +9 more
wiley   +1 more source

Novel Noninvasive Broad‐Spectrum Infrared Treatment of Ulcerative Colitis by Modulating T‐Cell Relocation

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A novel graphene‐based broad‐spectrum infrared (BSIR) device is developed for the noninvasive treatment of ulcerative colitis (UC). BSIR irradiation effectively alleviates colonic inflammation and accelerates mucosal recovery by inducing the systemic relocation of T lymphocytes to the spleen.
Siyu Chen   +15 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

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