Results 181 to 190 of about 20,572 (218)

Role of IFN-γ from Different Immune Cells in <i>Chlamydia</i> Infection. [PDF]

Microorganisms
Chen X, Yang W, Hu Y, Zhou Y, Zhou Z.
europepmc   +1 more source

Development of potential immunomodulatory ligands targeting natural killer T cells inspired by gut symbiont-derived glycolipids. [PDF]

Commun Chem
Lee J, Son S, Lee M, Park SB.
europepmc   +1 more source

Comparison of the effect of iguratimod and hydroxychloroquine on regulatory B cells in the treatment of primary Sjögren's syndrome. [PDF]

Front Med (Lausanne)
Zou JM, Yang L, Luo JA, Ren Y, Li SY, Zhang Y, Dong JL, Deng DH, Ni YP, Li M, Yin XS, Yang J.   +11 more
europepmc   +1 more source

Enhancing the iNKT cell immunotherapy platform by combining optimised CAR endodomains with novel iNKT engagers

Ponnusamy K, Karaxhuku K, Jiang Y, Randzavola L, Ren H, Leontari I, Lye B, Zaidi M, Bartlett EJ, Tate EW, Pardalis V, Leonardos D, Nadafi R, Sarkar I, Reijmers RM, Bua M, Atta M, Katsarou A, Roberts IA, Chaidos A, Karadimitris A.   +20 more
europepmc   +1 more source

The Role of Glycosphingolipids in Autoimmune Manifestations and Myeloma in Gaucher Disease

Pavlova E, Archer J, Guimaraes Da Lomba Ferraz M, Aerts J, Cox T, the MRC Gaucherite consortium.   +5 more
europepmc   +1 more source

CD1d-lipid antigen recognition by the γδ TCR [PDF]

Nature Immunology, 2013
The T lymphocytes repertoire is divided into two major lineages, αβ and γδ T cells, which are defined by their T cell receptor (TCR) gene-segment usage. To date, the key discoveries on human CD1d restricted T cells have focussed on the type I Natural Killer T cells (NKT) subset that express an invariant TCR α chain (Vα24Jα18) which pairs with a β chain
Adam P Uldrich, Jerome Le Nours, Daniel G Pellicci   +2 more
exaly   +4 more sources

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Adipocyte CD1d Gene Transfer Induces T Cell Expansion and Adipocyte Inflammation in CD1d Knockout Mice

The Journal of Immunology, 2022
Abstract CD1d, a lipid Ag-presenting molecule for invariant NKT (iNKT) cells, is abundantly expressed on adipocytes and regulates adipose homeostasis through iNKT cells. CD1d gene expression was restored in visceral adipose tissue adipocytes of CD1d knockout (KO) mice to investigate the interactions between adipocytes and immune cells ...
Run Xiao, Anthony G Mansour, Wei Huang, Quais N Hassan, Ryan K Wilkins, Suraj V Komatineni, Rhiannon Bates, Seemaab Ali, Logan A Chrislip, Nicholas J Queen, Shoubao Ma, Jianhua Yu, Matthew R Lordo, Bethany L Mundy-Bosse, Michael A Caligiuri, Lei Cao   +15 more
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Tissue-Specific Segregation of CD1d-Dependent and CD1d-Independent NK T Cells

The Journal of Immunology, 1999
AbstractNKT cells, defined as T cells expressing the NK cell marker NK1.1, are involved in tumor rejection and regulation of autoimmunity via the production of cytokines. We show in this study that two types of NKT cells can be defined on the basis of their reactivity to the monomorphic MHC class I-like molecule CD1d. One type of NKT cell is positively
Eberl, R, Lees, R, Smiley, S T, Taniguchi, M, Grusby, M J, Macdonald, H R   +5 more
openaire   +3 more sources

Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining [PDF]

Journal of Experimental Medicine, 2002
CD1d-restricted natural killer (NK)T cells are known to potently secrete T helper (Th)1 and Th2 cytokines and to mediate cytolysis, but it is unclear how these contrasting functional activities are regulated. Using lipid antigen–loaded CD1d tetramers, we have distinguished two subsets of CD1d-restricted T cells in fresh peripheral blood that differ in ...
Jenny E Gumperz
exaly   +3 more sources