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NKT Cell Responses to B Cell Lymphoma [PDF]
Medical Sciences, 2014 Natural killer T (NKT) cells are a unique subset of CD1d-restricted T lymphocytes that express characteristics of both T cells and natural killer cells.
Junxin Li +8 more
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Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines [PDF]
Vaccines, 2021 Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide range of the immune cells, including T cells, B cells, dendritic cells and macrophages.
Masood Alam Khan, Arif Khan
doaj +4 more sources
Nature Immunology, 2010 Natural killer T cells (NKT cells) are CD1d-restricted, lipid antigen–reactive, immunoregulatory T lymphocytes that can promote cell-mediated immunity to tumors and infectious organisms, including bacteria and viruses, yet paradoxically they can also ...
Dale I Godfrey +2 more
exaly +5 more sources
Control points in NKT-cell development
Nature Reviews Immunology, 2007 CD1d-dependent natural killer T (NKT) cells are a unique T-cell subset with the ability to regulate the immune system in response to a broad range of diseases. That low NKT-cell numbers are associated with many different disease states in mice and humans,
Dale I Godfrey, Berzins Stuart P
exaly +2 more sources
Frontiers in Cell and Developmental Biology, 2020 Vα24-invariant human natural killer T (NKT) cells comprise a unique subset of CD1d-restricted T cells with potent immune regulatory function and are involved in the development of a variety of human diseases.
Li Zhou +9 more
doaj +3 more sources
EBV promotes human CD8 NKT cell development. [PDF]
PLoS Pathogens, 2010 The reports on the origin of human CD8(+) Valpha24(+) T-cell receptor (TCR) natural killer T (NKT) cells are controversial. The underlying mechanism that controls human CD4 versus CD8 NKT cell development is not well-characterized.
Yuling He +14 more
doaj +2 more sources
Regulation of NKT cell localization in homeostasis and infection
Frontiers in Immunology, 2015 Natural killer T (NKT) cells are a specialized subset of T lymphocytes that regulate immune responses in the context of autoimmunity, cancer, and microbial infection.
Drew eSlauenwhite +3 more
doaj +2 more sources
NKT Cell Subsets Mediate Differential Proatherogenic Effects in ApoE −/− Mice
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 OBJECTIVE: NKT cells promote atherogenesis, but the subtypes responsible have not been identified. We investigated 2 major NKT cell subtypes (CD4(+) and DN NKT) in ApoE(-/-) mice rendered NKT cell-deficient by day-3 neonatal thymectomy (3dTx).
Gurdyal S Besra +2 more
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NKT cell networks in the regulation of tumor immunity
Frontiers in Immunology, 2014 CD1d-restricted natural killer T (NKT) cells lie at the interface between the innate and adaptive immune systems and are important mediators of immune responses and tumor immunosurveillance.
Faith C Robertson +2 more
doaj +3 more sources
NKT-cell subsets: Promoters and protectors in inflammatory liver disease
Journal of Hepatology, 2013 SummaryNatural killer T cells (NKT) are innate-like cells which are abundant in liver sinusoids and express the cell surface receptors of NK cells (e.g., NK1.1 (mouse) or CD161+/CD56+(human)) as well as an antigen receptor (TCR) characteristic of ...
Vipin Kumar
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