Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines [PDF]
Vaccines, 2021 Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide range of the immune cells, including T cells, B cells, dendritic cells and macrophages.
Masood Alam Khan, Arif Khan
doaj +6 more sources
Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency. [PDF]
PLoS ONE, 2017 Serum levels of choline and its derivatives are lower in patients with inflammatory bowel disease (IBD) than in healthy individuals. However, the effect of choline deficiency on the severity of colitis has not been investigated.
Shintaro Sagami +9 more
doaj +3 more sources
The surveillance of viral infections by the unconventional Type I NKT cell [PDF]
Frontiers in ImmunologyType I NKT cells, also known as Invariant Natural Killer T (iNKT) cells, are a subpopulation of unconventional, innate-like T (ILT) cells which can proficiently influence downstream immune effector functions.
Varshini Rajashekar +8 more
doaj +2 more sources
The Current Landscape of NKT Cell Immunotherapy and the Hills Ahead. [PDF]
Cancers (Basel), 2021 Nelson A, Lukacs JD, Johnston B.
europepmc +2 more sources
The interaction between regulatory T cells and NKT cells in the liver: a CD1d bridge links innate and adaptive immunity. [PDF]
PLoS ONE, 2011 Regulatory T cells (Tregs) and natural killer T (NKT) cells are two distinct lymphocyte subsets that independently regulate hepatic adaptive and innate immunity, respectively.
Jing Hua +5 more
doaj +1 more source
B-cell lymphopoiesis is regulated by cathepsin L. [PDF]
PLoS ONE, 2013 Cathepsin L (CTSL) is a ubiquitously expressed lysosomal cysteine peptidase with diverse and highly specific functions. The involvement of CTSL in thymic CD4+ T-cell positive selection has been well documented.
Maria Noel Badano +8 more
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Identification of CD4(-)CD8(-) double-negative natural killer T cell precursors in the thymus. [PDF]
PLoS ONE, 2008 BACKGROUND: It is well known that CD1d-restricted Valpha14 invariant natural killer T (NKT) cells are derived from cells in the CD4(+)CD8(+) double-positive (DP) population in the thymus. However, the developmental progression of NKT cells in the earlier
Nyambayar Dashtsoodol +3 more
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Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions. [PDF]
PLoS ONE, 2006 Natural killer T (NKT) cells are a subset of T cells that help potentiate and regulate immune responses. Although human NKT cell subsets with distinct effector functions have been identified, it is unclear whether the effector functions of these subsets ...
Karla A Eger +5 more
doaj +1 more source
Natural killer T cell and pathophysiology of asthma [PDF]
Korean Journal of Pediatrics, 2010 Natural killer T (NKT) cell is a special type of T lymphocytes that has both receptor of natural killer (NK) cell (NK1.1, CD161c) and T cell (TCR) and express a conserved or invariant T cell receptor called V?#7284;J?#7288; in mice or Va24 in humans ...
Gwang Cheon Jang
doaj +1 more source
Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells. [PDF]
PLoS ONE, 2015 Cell-based therapies using genetically engineered lymphocytes expressing antigen-specific T cell receptors (TCRs) hold promise for the treatment of several types of cancers.
Kanako Shimizu +8 more
doaj +1 more source