Results 31 to 40 of about 5,157 (213)
NKT Cells Contribute to the Control of Microbial Infections
Frontiers in Cellular and Infection Microbiology, 2021 Innate (-like) T lymphocytes such as natural killer T (NKT) cells play a pivotal role in the recognition of microbial infections and their subsequent elimination.
Stefan Vogt +2 more
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Description of invariant NKT cells.
Journal of Education, Health and Sport, 2021 Recently discovered subpopulations belonging to cell groups called “invariant” NKT, also referred to as type I NKT or classical NKT cells, appear to have a unique impact on the tumor microenvironment. Considering the characteristics of secreted cytokines, production of chemokines and the capability of cell cytotoxic activity, these cells have a ...
Katarzyna Karwicka +2 more
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Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
The Role of Natural Killer T Cells in Cancer—A Phenotypical and Functional Approach
Frontiers in Immunology, 2018 Natural killer T (NKT) cells are a subset of CD1d-restricted T cells at the interface between the innate and adaptive immune system. NKT cells can be subdivided into functional subsets that respond rapidly to a wide variety of glycolipids and stress ...
Daniëlle Krijgsman +3 more
doaj +1 more source
, 2021 Drugs selectively targeting replication stress have demonstrated significant preclinical activity, but this has not yet translated into an effective clinical treatment.
Keane, C +12 more
core +1 more source
Frontiers in Immunology, 2018 Vaccination with CD1d-binding glycolipid adjuvants and co-administered protein, lipid, and carbohydrate antigens leads to invariant natural killer T (NKT) cell-dependent enhancement of protective B cell responses.
Mark L. Lang
doaj +1 more source
NK and NKT cell functions in immunosenescence [PDF]
, 2004 Immunosenescence is defined as the state of dysregulated immune function that contributes to the increased susceptibility to infection, cancer and autoimmune diseases observed in old organisms, including humans.
Malavolta M., Mocchegiani E.
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Betting on NKT and NK Cells [PDF]
Immunity, 2004 Natural killer T (NKT) cells, as their name implies, constitutively express markers and receptors first identified on bona fide natural killer (NK) cells, supporting a potential relationship between NKT and NK cells. In this issue of Immunity, Townsend et al. further define this relationship in terms of the transcription factor, T-bet.
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Frontiers in Immunology, 2018 Natural killer T (NKT) cells are a unique T cell subset that exhibits characteristics from both the innate immune cells and T cells. There are at least two subsets of NKT cells, type I and type II.
Shingo Kato +2 more
doaj +1 more source
NKT cells in cardiovascular diseases
European Journal of Pharmacology, 2017 Despite life-style advice and the prescription of cholesterol-lowering and anti-thrombotic drugs, cardiovascular diseases are still the leading cause of death worldwide. Therefore, there is an urgent need for new therapeutic strategies focussing on atherosclerosis, the major underlying pathology of cardiovascular diseases characterized by an ...
Puijvelde, G.H.M. van, Kuiper, J.
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