NKT cells in the antitumor response: the β version? [PDF]
The Journal of Clinical InvestigationNKT cells recognize glycolipids presented by CD1d-expressing antigen-presenting cells (APCs) and include type I NKT cells with antitumor function and type II NKT cells, which have been reported to suppress the antitumor response.
Mitchell Kronenberg, Isaac Engel
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Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines
Vaccines, 2021 Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide range of the immune cells, including T cells, B cells, dendritic cells and macrophages.
Masood Alam Khan, Arif Khan
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Cord blood Vα24-Vβ11 natural killer T cells display a Th2-chemokine receptor profile and cytokine responses. [PDF]
PLoS ONE, 2011 BACKGROUND: The fetal immune system is characterized by a Th2 bias but it is unclear how the Th2 predominance is established. Natural killer T (NKT) cells are a rare subset of T cells with immune regulatory functions and are already activated in utero ...
Susanne Harner +7 more
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Mendelian Randomization and Transcriptomic Analysis Reveal the Protective Role of NKT Cells in Sepsis [PDF]
Journal of Inflammation ResearchQingxiang Liu,1,* Haitao Liu,2,* Zihan Hu,1 Xing Zhou,1 Kai Jin,1 Yingzi Huang,1 Wei Huang,1 Yi Yang1 1Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine ...
Liu Q +7 more
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Novel lipid antigens for NKT cells in cancer [PDF]
Frontiers in Immunology, 2023 Michael Lee, Tonya Webb
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OncoImmunology, 2021 CD3+CD56+ NKT-like cells play pivotal roles in the anti-tumor immune defense response. However, little is known regarding circulating NKT-like cells in patients with primary hepatocellular carcinoma (HCC).
Longxiang Tao +7 more
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Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions. [PDF]
PLoS ONE, 2006 Natural killer T (NKT) cells are a subset of T cells that help potentiate and regulate immune responses. Although human NKT cell subsets with distinct effector functions have been identified, it is unclear whether the effector functions of these subsets ...
Karla A Eger +5 more
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Identification of CD4(-)CD8(-) double-negative natural killer T cell precursors in the thymus. [PDF]
PLoS ONE, 2008 BACKGROUND: It is well known that CD1d-restricted Valpha14 invariant natural killer T (NKT) cells are derived from cells in the CD4(+)CD8(+) double-positive (DP) population in the thymus. However, the developmental progression of NKT cells in the earlier
Nyambayar Dashtsoodol +3 more
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The interaction between regulatory T cells and NKT cells in the liver: a CD1d bridge links innate and adaptive immunity. [PDF]
PLoS ONE, 2011 Regulatory T cells (Tregs) and natural killer T (NKT) cells are two distinct lymphocyte subsets that independently regulate hepatic adaptive and innate immunity, respectively.
Jing Hua +5 more
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Frontiers in Immunology, 2018 Natural killer T (NKT) cells are a unique T cell subset that exhibits characteristics from both the innate immune cells and T cells. There are at least two subsets of NKT cells, type I and type II.
Shingo Kato +2 more
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