Results 21 to 30 of about 4,443,105 (228)

NKT Cell Responses to B Cell Lymphoma

Medical Sciences, 2014
Natural killer T (NKT) cells are a unique subset of CD1d-restricted T lymphocytes that express characteristics of both T cells and natural killer cells.
Junxin Li, Wenji Sun, Priyanka B. Subrahmanyam, Carly Page, Kenisha M. Younger, Irina V. Tiper, Matthew Frieman, Amy S. Kimball, Tonya J. Webb   +8 more
doaj   +1 more source

Roles and therapeutic potential of CD1d-Restricted NKT cells in inflammatory skin diseases

Frontiers in Immunology, 2022
Natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens rather than peptides. Due to their immunoregulatory properties, extensive work has been done to elucidate the immune functions of NKT cells in various immune ...
Sung Won Lee, Hyun Jung Park, Luc Van Kaer, Seokmann Hong   +3 more
doaj   +1 more source

Type II Natural Killer T Cells Contribute to Protection Against Systemic Methicillin-Resistant Staphylococcus aureus Infection

Frontiers in Immunology, 2020
Methicillin-resistant Staphylococcus aureus (SA) bacteremia is responsible for over 10,000 deaths in the hospital setting each year. Both conventional CD4+ T cells and γδ T cells play protective roles in SA infection through secretion of IFN-γ and IL-17.
Samantha Genardi, Lavanya Visvabharathy, Liang Cao, Eva Morgun, Yongyong Cui, Chao Qi, Yi-Hua Chen, Laurent Gapin, Evgeny Berdyshev, Chyung-Ru Wang   +9 more
doaj   +1 more source

Assessing the response of T cells to "Mycobacterium tuberculosis" lipids [PDF]

, 2008
Most vaccines used nowadays are created using inactivated or attenuated compounds from micro-organisms. Advances in basic immunology and molecular biology opened the gate for consequent improvement of vaccination strategies.
Collmann, Anthony
core   +1 more source

Intrahepatic CD8+ lymphocyte trapping during tolerance induction using mushroom derived formulations: A possible role for liver in tolerance induction [PDF]

, 2008
AIM: To determine the immunomodulatory effect of Shiitake (a mushroom extract), we tested its effect on liver-mediated immune regulation in a model of immune-mediated colitis. METHODS: Four groups of mice were studied. Colitis was induced by intracolonic
Hershcovici, T., Lidya Zolotarov, Shuvy, M., Mony Shuvy, Cristina Lull-Noguera, Lull-Noguera, C., Tiberiu Hershcovici, Wichers, H.J., Dan Levanon, Harry Wichers, Yaron Ilan, Ofer Danay   +11 more
core   +1 more source

Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death. [PDF]

PLoS ONE, 2013
BACKGROUND: Dietary lipids play an important role in the progression of non-alcoholic fatty liver disease (NAFLD) through alternation of liver innate immune response.
Tongfang Tang, Yongheng Sui, Min Lian, Zhiping Li, Jing Hua   +4 more
doaj   +1 more source

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias [PDF]

, 2014
T cells that recognize self-lipids presented by CD1c are frequent in the peripheral blood of healthy individuals and kill transformed hematopoietic cells, but little is known about their antigen specificity and potential antileukemia effects.
Lepore, Marco, Locatelli, Franco, Giulia Casorati, Paul Jenö, Chengfeng Xia, Consonni, Michela, S. R. Gundimeda, P. Jeno, Daniela Montagna, C. Bonini, Alessandra Forcina, G. Casorati, Claudia de Lalla, Franco Locatelli, Sansano, Sebastiano, Bonini, Chiara, Piccolo, Francesco, Xia, Chengfeng, Z. Li, P. Dellabona, Garavaglia, Claudio, H. Gsellinger, F. Piccolo, de Lalla, Claudia, Paolo Dellabona, G. Ni, F. Ciceri, Gundimeda, S. Ramanjaneyulu, Heiko Gsellinger, Häussinger, Daniel, Daniel Häussinger, Scelfo, Andrea, L. Mori, C. Garavaglia, Gennaro De Libero, A. Bondanza, Michela Consonni, Sebastiano Sansano, A. Forcina, Ciceri, Fabio, Jenö, Paul, Fabio Ciceri, M. Lepore, Attilio Bondanza, Gsellinger, Heiko, De Libero, Gennaro, S. Sansano, Bondanza, Attilio, Casorati, Giulia, D. Haussinger, Marco Lepore, C. de Lalla, G. De Libero, M. Consonni, Guanghui Ni, Lucia Mori, Li, Zhiyuan, Zhiyuan Li, Montagna, Daniela, Forcina, Alessandra, Andrea Scelfo, Mori, Lucia, S. Ramanjaneyulu Gundimeda, Chiara Bonini, Claudio Garavaglia, A. Scelfo, Francesco Piccolo, Ni, Guanghui, C. Xia, Dellabona, Paolo   +69 more
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Cytotoxic activity of invariant NKT cells in human allergic contact dermatitis [PDF]

, 2009
Cytotoxic activity of invariant NKT cells in human allergic contact dermatitis Background: The role of cytotoxicity of NKT-cells in the skin is not defined. There are two prototypic skin diseases in which epidermal Keratinocytes (KC) over-express CD1d, a
Balato, Anna
core   +1 more source

Natural Killer T Cells Are Numerically and Functionally Deficient in Patients with Trauma

Journal of Innate Immunity, 2020
Natural killer T (NKT) cells rapidly produce Th1 and Th2 cytokines such as interferon-γ (IFN-γ) and interleukin (IL)-4. This study examined the frequency and function of NKT cells in trauma patients.
Young-Goun  Jo, Jung-Chul  Kim, Hye-Mi  Jin, Young-Nan  Cho, Seung-Jung  Kee, Yong-Wook Park   +5 more
doaj   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source