Results 11 to 20 of about 35,995 (263)
Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines [PDF]
Vaccines, 2021 Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide range of the immune cells, including T cells, B cells, dendritic cells and macrophages.
Masood Alam Khan, Arif Khan
doaj +6 more sources
NKT Cells in Neurological Diseases [PDF]
Frontiers in Cellular Neuroscience, 2019 Natural killer T (NKT) cells are a unique subset of T lymphocytes with the expression of T cell receptor (TCR) and NK cell lineage receptors. These cells can rapidly release large quantities of cytokines and function as a bridge between innate and ...
Yu Cui, Qi Wan
doaj +4 more sources
NKT cells in the antitumor response: the β version? [PDF]
The Journal of Clinical InvestigationNKT cells recognize glycolipids presented by CD1d-expressing antigen-presenting cells (APCs) and include type I NKT cells with antitumor function and type II NKT cells, which have been reported to suppress the antitumor response.
Mitchell Kronenberg, Isaac Engel
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Cord blood Vα24-Vβ11 natural killer T cells display a Th2-chemokine receptor profile and cytokine responses. [PDF]
PLoS ONE, 2011 BACKGROUND: The fetal immune system is characterized by a Th2 bias but it is unclear how the Th2 predominance is established. Natural killer T (NKT) cells are a rare subset of T cells with immune regulatory functions and are already activated in utero ...
Susanne Harner +7 more
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Tissue-Specific Roles of NKT Cells in Tumor Immunity
Frontiers in Immunology, 2018 NKT cells are an unusual population of T cells recognizing lipids presented by CD1d, a non-classical class-I-like molecule, rather than peptides presented by conventional MHC molecules. Type I NKT cells use a semi-invariant T cell receptor and almost all
Masaki Terabe, Jay A. Berzofsky
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The Role of NKT Cells in Glioblastoma. [PDF]
Cells, 2021 Glioblastoma is an aggressive and deadly cancer, but to date, immunotherapies have failed to make significant strides in improving prognoses for glioblastoma patients.
Brettschneider EES, Terabe M.
europepmc +6 more sources
Clinical & developmental immunology, 2010 Sepsis is currently a leading cause of death in hospital intensive care units. Previous studies suggest that the pathophysiology of sepsis involves the hyperactivation of complex proinflammatory cascades that include the activation of various immune ...
Briana Leung +3 more
core +6 more sources
Betting on NKT and NK Cells [PDF]
Immunity, 2004 Natural killer T (NKT) cells, as their name implies, constitutively express markers and receptors first identified on bona fide natural killer (NK) cells, supporting a potential relationship between NKT and NK cells.
Yokoyama, Wayne M
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Therapeutic approaches utilising NKT cells
Proceedings of the Japan Academy, Series B, 2011 Natural killer T (NKT) cells are members of the immune armamentarium with profound immunoregulatory effects. They bridge the innate and adaptive immune systems, filling a niche in recognizing glycolipid antigens, and responding rapidly to prime ...
Smyth, Mark J. +3 more
core +4 more sources
NKT Cell Responses to B Cell Lymphoma [PDF]
Medical Sciences, 2014 Natural killer T (NKT) cells are a unique subset of CD1d-restricted T lymphocytes that express characteristics of both T cells and natural killer cells.
Junxin Li +8 more
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