Results 11 to 20 of about 30,945 (225)
Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines [PDF]
Vaccines, 2021 Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide range of the immune cells, including T cells, B cells, dendritic cells and macrophages.
Masood Alam Khan, Arif Khan
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Roles and therapeutic potential of CD1d-Restricted NKT cells in inflammatory skin diseases [PDF]
Frontiers in Immunology, 2022 Natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens rather than peptides. Due to their immunoregulatory properties, extensive work has been done to elucidate the immune functions of NKT cells in various immune ...
Sung Won Lee +3 more
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NKT cells in the antitumor response: the β version? [PDF]
The Journal of Clinical InvestigationNKT cells recognize glycolipids presented by CD1d-expressing antigen-presenting cells (APCs) and include type I NKT cells with antitumor function and type II NKT cells, which have been reported to suppress the antitumor response.
Mitchell Kronenberg, Isaac Engel
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NKT Cell Responses to B Cell Lymphoma [PDF]
Medical Sciences, 2014 Natural killer T (NKT) cells are a unique subset of CD1d-restricted T lymphocytes that express characteristics of both T cells and natural killer cells.
Junxin Li +8 more
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NKT Cells in Neurological Diseases [PDF]
Frontiers in Cellular Neuroscience, 2019 Natural killer T (NKT) cells are a unique subset of T lymphocytes with the expression of T cell receptor (TCR) and NK cell lineage receptors. These cells can rapidly release large quantities of cytokines and function as a bridge between innate and ...
Yu Cui, Qi Wan
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Frontiers in Immunology, 2019 Background: Natural Killer T (NKT) cells are CD1d-restricted innate-like T cells that can rapidly release stored cytokines upon recognition of lipid antigens. In mice, type I NKT cells seem to promote liver inflammation, whereas type II NKT cells seem to
Marcial Sebode +21 more
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Tissue-Specific Roles of NKT Cells in Tumor Immunity
Frontiers in Immunology, 2018 NKT cells are an unusual population of T cells recognizing lipids presented by CD1d, a non-classical class-I-like molecule, rather than peptides presented by conventional MHC molecules. Type I NKT cells use a semi-invariant T cell receptor and almost all
Masaki Terabe, Jay A. Berzofsky
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Mendelian Randomization and Transcriptomic Analysis Reveal the Protective Role of NKT Cells in Sepsis [PDF]
Journal of Inflammation ResearchQingxiang Liu,1,* Haitao Liu,2,* Zihan Hu,1 Xing Zhou,1 Kai Jin,1 Yingzi Huang,1 Wei Huang,1 Yi Yang1 1Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine ...
Liu Q +7 more
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The Role of NKT Cells in Glioblastoma. [PDF]
Cells, 2021 Glioblastoma is an aggressive and deadly cancer, but to date, immunotherapies have failed to make significant strides in improving prognoses for glioblastoma patients. One of the current challenges to developing immunological interventions for glioblastoma is our incomplete understanding of the numerous immunoregulatory mechanisms at play in the ...
Brettschneider EES, Terabe M.
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Harnessing NKT cells for vaccination. [PDF]
Oxf Open Immunol, 2021 Lay Summary Vaccine-induced immune responses generally involve activation of immune cells called T and B cells that have a variety of mechanisms to limit the infection. Each T or B cell has a randomly generated receptor for binding pathogen-derived antigens, but only a few cells with an individual’s repertoire of cells will recognize a ...
Burn OK +4 more
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