Results 11 to 20 of about 58,157 (254)
Identification of CD4(-)CD8(-) double-negative natural killer T cell precursors in the thymus. [PDF]
PLoS ONE, 2008 BACKGROUND: It is well known that CD1d-restricted Valpha14 invariant natural killer T (NKT) cells are derived from cells in the CD4(+)CD8(+) double-positive (DP) population in the thymus. However, the developmental progression of NKT cells in the earlier
Nyambayar Dashtsoodol +3 more
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The interaction between regulatory T cells and NKT cells in the liver: a CD1d bridge links innate and adaptive immunity. [PDF]
PLoS ONE, 2011 Regulatory T cells (Tregs) and natural killer T (NKT) cells are two distinct lymphocyte subsets that independently regulate hepatic adaptive and innate immunity, respectively.
Jing Hua +5 more
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Description of invariant NKT cells.
Journal of Education, Health and Sport, 2021 Recently discovered subpopulations belonging to cell groups called “invariant” NKT, also referred to as type I NKT or classical NKT cells, appear to have a unique impact on the tumor microenvironment. Considering the characteristics of secreted cytokines, production of chemokines and the capability of cell cytotoxic activity, these cells have a ...
Katarzyna Karwicka +2 more
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Cord blood Vα24-Vβ11 natural killer T cells display a Th2-chemokine receptor profile and cytokine responses. [PDF]
PLoS ONE, 2011 BACKGROUND: The fetal immune system is characterized by a Th2 bias but it is unclear how the Th2 predominance is established. Natural killer T (NKT) cells are a rare subset of T cells with immune regulatory functions and are already activated in utero ...
Susanne Harner +7 more
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Clinical & developmental immunology, 2010 Sepsis is currently a leading cause of death in hospital intensive care units. Previous studies suggest that the pathophysiology of sepsis involves the hyperactivation of complex proinflammatory cascades that include the activation of various immune cells and the exuberant secretion of proinflammatory cytokines by these cells.
Leung, Briana, Harris, Hobart W
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Frontiers in Immunology, 2018 Natural killer T (NKT) cells are a unique T cell subset that exhibits characteristics from both the innate immune cells and T cells. There are at least two subsets of NKT cells, type I and type II.
Shingo Kato +2 more
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Immunobiology, 2017 The role of NKT cells in the resistance or susceptibility towards Leishmania infections remains to be defined, since controversial data persist. The response of these cells seems to depend on many variables such as the infection site, the number of infecting parasites, the virulence of the strain and the Leishmania species.
Jaime, Zamora-Chimal +2 more
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Immune evasion of the CD1d/NKT cell axis [PDF]
, 2018 Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity.
Brutkiewicz, Randy R. +2 more
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ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids [PDF]
, 2020 CD1d-restricted invariant natural killer T (iNKT) cells constitute a common glycolipid-reactive innate-like T-cell subset with a broad impact on innate and adaptive immunity.
Cheng, Tan‐Yun +12 more
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The Role of Natural Killer T Cells in Cancer—A Phenotypical and Functional Approach
Frontiers in Immunology, 2018 Natural killer T (NKT) cells are a subset of CD1d-restricted T cells at the interface between the innate and adaptive immune system. NKT cells can be subdivided into functional subsets that respond rapidly to a wide variety of glycolipids and stress ...
Daniëlle Krijgsman +3 more
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