Results 11 to 20 of about 5,685,226 (248)
NKT cells in the antitumor response: the β version? [PDF]
The Journal of Clinical InvestigationNKT cells recognize glycolipids presented by CD1d-expressing antigen-presenting cells (APCs) and include type I NKT cells with antitumor function and type II NKT cells, which have been reported to suppress the antitumor response.
Mitchell Kronenberg, Isaac Engel
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Natural Killer T (NKT) Cells in Autoimmune Hepatitis: Current Evidence from Basic and Clinical Research. [PDF]
Cells, 2023 Natural killer T (NKT) cells are unconventional T cells that are activated by glycolipid antigens. They can produce a variety of inflammatory and regulatory cytokines and, therefore, modulate multiple aspects of the immune response in different ...
Dimitri Poddighe +4 more
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Invariant NKT Cells as Novel Targets for Immunotherapy in Solid Tumors [PDF]
Clinical and Developmental Immunology, 2012 Natural killer T (NKT) cells are a small population of lymphocytes that possess characteristics of both innate and adaptive immune cells. They are uniquely poised to respond rapidly to infection and inflammation and produce cytokines that critically ...
Karsten A. Pilones +2 more
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Cross-talk between cd1d-restricted nkt cells and γδ cells in t regulatory cell response [PDF]
Virology Journal, 2011 CD1d is a non-classical major histocompatibility class 1-like molecule which primarily presents either microbial or endogenous glycolipid antigens to T cells involved in innate immunity.
Huber Sally A, Liu Wei
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Contribution of NKT cells and CD1d-expressing cells in obesity-associated adipose tissue inflammation [PDF]
Frontiers in ImmunologyNatural killer T (NKT) cell are members of the innate-like T lymphocytes and recognizes lipid antigens presented by CD1d-expressing cells. Obesity-associated inflammation in adipose tissue (AT) leads to metabolic dysfunction, including insulin resistance.
Masashi Satoh, Kazuya Iwabuchi
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[Retracted] NKT Cells in Sepsis [PDF]
Journal of Immunology Research, 2010 Sepsis is currently a leading cause of death in hospital intensive care units. Previous studies suggest that the pathophysiology of sepsis involves the hyperactivation of complex proinflammatory cascades that include the activation of various immune cells and the exuberant secretion of proinflammatory cytokines by these cells.
Leung, Briana, Harris, Hobart W
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OncoImmunology, 2021 CD3+CD56+ NKT-like cells play pivotal roles in the anti-tumor immune defense response. However, little is known regarding circulating NKT-like cells in patients with primary hepatocellular carcinoma (HCC).
Longxiang Tao +7 more
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Mendelian Randomization and Transcriptomic Analysis Reveal the Protective Role of NKT Cells in Sepsis [PDF]
Journal of Inflammation ResearchQingxiang Liu,1,* Haitao Liu,2,* Zihan Hu,1 Xing Zhou,1 Kai Jin,1 Yingzi Huang,1 Wei Huang,1 Yi Yang1 1Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine ...
Liu Q +7 more
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Regulation of NKT Cells by Ly49: Analysis of Primary NKT Cells and Generation of NKT Cell Line [PDF]
The Journal of Immunology, 2001 Abstract TCRαβ+NK1.1+ (NKT) cells are known to express various NK cell-associated molecules including the Ly49 family of receptors for MHC class I, but its functional significance has been unclear. Here, we examined the expression of Ly49A, C/I and G2 on various NKT cell populations from normal and MHC class I-deficient C57BL/6 mice ...
M, Maeda +3 more
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Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions. [PDF]
PLoS ONE, 2006 Natural killer T (NKT) cells are a subset of T cells that help potentiate and regulate immune responses. Although human NKT cell subsets with distinct effector functions have been identified, it is unclear whether the effector functions of these subsets ...
Karla A Eger +5 more
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