Results 11 to 20 of about 180,829 (383)
CD19 and CD20 Targeted Vectors Induce Minimal Activation of Resting B Lymphocytes [PDF]
, 2013 B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
Sabrina Kneissl +5 more
core +12 more sources
The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy
Haematologica, 2020 The introduction of anti-CD20 monoclonal antibodies such as rituximab, ofatumumab, or obinutuzumab improved the therapy of B-cell malignancies even though the precise physiological role and regulation of CD20 remains unclear. Furthermore, CD20 expression
Gabriela Pavlasova, Marek Mraz
doaj +2 more sources
Surface levels of CD20 determine anti-CD20 antibodies mediated cell death in vitro. [PDF]
PLoS ONE, 2014 The sensitivity of human Burkitt's lymphoma cells to rituximab (Rtx) and tositumomab (Tst) was assessed on cells expressing different levels of CD20 on surface.
Vijay Singh +5 more
doaj +4 more sources
A CCL5+CD20+CD8+ T cell subset drives pathogenic transformation of synoviocytes in rheumatoid arthritis via JAK-STAT signaling [PDF]
Cell & BioscienceBackground In rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLS) acquire an aggressive phenotype promoting inflammation and joint damage. While FLS interactions with recruited T cells are established, drivers of FLS aggressiveness and the role
Haonan Jia +12 more
doaj +2 more sources
Journal of Translational MedicineBackground Chimeric antigen receptor natural killer (CAR-NK) cells represent a promising advancement in CAR cell therapy, addressing limitations observed in CAR-T cell therapy.
Na Yang +11 more
doaj +2 more sources
Клиническая онкогематологияAim. To assess the prognostic value of CD20-positive B-lymphocytes in the reactive tumor microenvironment using histological specimens of lymph nodes from patients with nodular sclerosis classical Hodgkin lymphoma (cHL). Materials & Methods.
Maksim Sergeevich Minaev
doaj +3 more sources
Scientific Reports, 2021 The presence of T cells that are dimly positive for the B cell marker CD20 is well-established in autoimmunity and correlates with disease severity in various diseases.
Martijn Vlaming +8 more
doaj +2 more sources
The efficacy and safety of anti-CD20 antibody for the treatment of B-ALL: a systematic review and meta-analysis. [PDF]
Ther Adv HematolZhou X +5 more
europepmc +2 more sources
CD4 and CD20 as important immune markers in patients with pulmonary tuberculosis [PDF]
E3S Web of Conferences, 2023 Tuberculosis (TB) is a serious lung infection caused by the bacterium Mycobacterium tuberculosis (M. tuberculosis) is highly contagious, and can be spread through the air from an infected person to others.
Kamoona Firas Mohammad Hussein +1 more
doaj +1 more source
Anti-CD20 therapies in multiple sclerosis: From pathology to the clinic
Frontiers in Immunology, 2023 The immune system plays a significant role in multiple sclerosis. While MS was historically thought to be T cell-mediated, multiple pieces of evidence now support the view that B cells are essential players in multiple sclerosis pathogenic processes ...
J. de Seze +9 more
semanticscholar +1 more source