Results 21 to 30 of about 106,748 (296)
GAS5 Long Noncoding RNA Regulates CD20 Expression and Rituximab Response [PDF]
Advanced Pharmaceutical BulletinPurpose: Rituximab is the primary treatment for non-Hodgkin lymphoma (NHL), one of the most common cancers globally. One of the main challenges associated with rituximab therapy is the decline in its effectiveness over time.
Mahbubeh Rojhannezhad +3 more
doaj +1 more source
Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)
Креативная хирургия и онкология, 2020 This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov +2 more
doaj +1 more source
Antibodies, 2022 This study aimed to investigate PD-L1 and PD-1 expression in circulating CD20+ cells in diffuse larger B-cell lymphoma (DLBCL) and to evaluate the predictive and diagnostic performance of PD-L1 versus PD-1 expression in circulating CD20+ cells in DLBCL ...
Manal Mohamed Saber
doaj +1 more source
CD89-mediated recruitment of macrophages via a bispecific antibody enhances anti-tumor efficacy
OncoImmunology, 2018 Since tumors are often infiltrated by macrophages, it would be advantageous to turn these types of cells into cytotoxic effector cells. Here, we have designed a novel bispecific antibody (BsAb) that targets both tumor antigen (CD20) and the FcαRI ...
Bingyu Li +8 more
doaj +1 more source
CD20+B LYMPHOCYTES, A HIGHLY INFORMATIVE BIOMARKER FOR EARLY DIAGNOSIS OF CHRONIC ENDOMETRITIS
Медицинская иммунология, 2019 Plasma cells are often considered to be among important criteria in histological diagnosis of chronic endometritis (CE). Low plasma cell numbers in endometrial stroma, uneven distribution and similarity to the cells of cytogenic endometrial stroma ...
V. N. Ellinidi +4 more
doaj +1 more source
Journal of Inflammation Research, 2023 Ping Lu,1 Lingyun Cui,1 Xinghu Zhang2 1Center for Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People’s Republic of China; 2Department of Neuroinfection and Neuroimmunology, Center for Neurology, Beijing Tiantan ...
Lu P, Cui L, Zhang X
doaj
Mouse CD20 expression and function [PDF]
International Immunology, 2004 CD20 plays a role in human B cell proliferation and is an effective target for immunotherapy. In this study, mouse CD20 expression and biochemistry were assessed for the first time using a new panel of CD20-specific mAb, with CD20 function assessed using CD20-deficient (CD20(-/-)) mice.
Junji, Uchida +10 more
openaire +2 more sources
Blood and Lymphatic Cancer: Targets and Therapy, 2023 Jing Wang,1 Firas Baidoun,2 Han W Tun,2 Muhamad Alhaj Moustafa2 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL, 32224, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic Florida, Jacksonville, FL, 32224 ...
Wang J +3 more
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Вопросы современной педиатрии, 2013 Aim: to assess efficacy and safety of rituximab treatment in children with systemic juvenile idiopathic arthritis under prolonged follow-up. Patients and methods: results of treatment of 60 children (33 girls and 27 boys) with systemic variant of ...
E. I. Alexeeva +10 more
doaj +1 more source
Veterinary Immunology and Immunopathology, 2005 The human CD20 antigen, a 35kDa cell surface nonglycosylated hydrophobic phoshpoprotein is expressed consistently on almost all human B-cells, and its monoclonal antibody is used for the therapy on human B-cell lymphoma. In the present study, canine CD20 gene was cloned and sequenced, and the expression of CD20 mRNA was investigated in canine ...
Rui, Kano +7 more
openaire +5 more sources