Results 51 to 60 of about 180,829 (383)
CD89-mediated recruitment of macrophages via a bispecific antibody enhances anti-tumor efficacy
OncoImmunology, 2018 Since tumors are often infiltrated by macrophages, it would be advantageous to turn these types of cells into cytotoxic effector cells. Here, we have designed a novel bispecific antibody (BsAb) that targets both tumor antigen (CD20) and the FcαRI ...
Bingyu Li +8 more
doaj +1 more source
CD20+B LYMPHOCYTES, A HIGHLY INFORMATIVE BIOMARKER FOR EARLY DIAGNOSIS OF CHRONIC ENDOMETRITIS
Медицинская иммунология, 2019 Plasma cells are often considered to be among important criteria in histological diagnosis of chronic endometritis (CE). Low plasma cell numbers in endometrial stroma, uneven distribution and similarity to the cells of cytogenic endometrial stroma ...
V. N. Ellinidi +4 more
doaj +1 more source
Humoral and cellular responses after COVID-19 vaccination in anti-CD20-treated lymphoma patients
Blood, 2021 Patients with hematological neoplasms, including lymphoma patients, have a high risk for severe COVID-19 diseases. COVID-19 vaccinations induce strong serologic and T-cell responses in immunocompetent humans and thereby effec-tively prevent severe COVID ...
Nora Liebers +11 more
semanticscholar +1 more source
Journal of Inflammation Research, 2023 Ping Lu,1 Lingyun Cui,1 Xinghu Zhang2 1Center for Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People’s Republic of China; 2Department of Neuroinfection and Neuroimmunology, Center for Neurology, Beijing Tiantan ...
Lu P, Cui L, Zhang X
doaj
CD20-targeting in B-cell malignancies: novel prospects for antibodies and combination therapies [PDF]
, 2016 Expression of CD20 antigen by the most of transformed B cells is believed to be the driving force for targeting this molecule by using anti-CD20 monoclonal antibodies. While it is true that most lymphoma/leukemia patients can be cured, these regimens are
Ahmadzadeh, V. +2 more
core +1 more source
Optimized tandem CD19/CD20 CAR-engineered T cells in refractory/relapsed B cell lymphoma.
Blood, 2020 Chimeric antigen receptor T (CAR T) cells targeting CD19 have achieved breakthroughs in the treatment of hematological malignancies, such as relapsed/refractory non-Hodgkin lymphoma (r/rNHL); however, high rates of treatment failure and recurrence after ...
Chuan Tong +14 more
semanticscholar +1 more source
Blood and Lymphatic Cancer: Targets and Therapy, 2023 Jing Wang,1 Firas Baidoun,2 Han W Tun,2 Muhamad Alhaj Moustafa2 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL, 32224, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic Florida, Jacksonville, FL, 32224 ...
Wang J +3 more
doaj
Вопросы современной педиатрии, 2013 Aim: to assess efficacy and safety of rituximab treatment in children with systemic juvenile idiopathic arthritis under prolonged follow-up. Patients and methods: results of treatment of 60 children (33 girls and 27 boys) with systemic variant of ...
E. I. Alexeeva +10 more
doaj +1 more source
Quantifying tumour-infiltrating lymphocyte subsets : a practical immuno-histochemical method [PDF]
, 2007 Background: Efficient histological quantification of tumour-infiltrating T and B lymphocyte (TIL) subsets in archival tissues would greatly facilitate investigations of the role of TIL in human cancer biology. We sought to develop such a method. Methods:
Alison J. Gray +19 more
core +1 more source
Brown Journal of Hospital Medicine, 2022 A woman in her 50s presented with hyper-religiosity, auditory hallucinations, episodes of staring associated with unresponsiveness and stiffening of her entire body. A broad workup excluded autoimmune encephalitis, sarcoidosis, and prion disease. She was
Carlin Chuck +2 more
doaj +1 more source