Integrated workflow of domoic acid (DA) detection in seafood using a high‐sensitivity electrochemical biosensor and subsequent evaluation of DA‐induced cellular responses. (A) DA monitoring in seafood: Marine samples (European anchovy and mussels from the Marmara and Black Sea) were collected, extracted using a 1:1 methanol/water mixture, and analyzed ...
Emilia Qomi Ekenel +10 more
wiley +1 more source
Delineating phenotypic heterogeneity in human regulatory T cells across developmental stages and therapeutic sources. [PDF]
Santosh Nirmala S +7 more
europepmc +1 more source
LZ‐8 reduced IL‐6 and COX‐2 in LPS‐stimulated macrophages, partly by inhibiting MyD88‐mediated JNK‐MAPK signaling. LZ‐8 reduced inflammation and swelling in the ankle and palm of the feet in the animal model. High‐dose LZ‐8 reduced synovial hyperplasia, and all doses protected articular cartilage.
Shao‐Wen Hung +3 more
wiley +1 more source
Design and Screening of the Peptide SAMP-12aa Derived from LL-37, Which Exhibits Anti-<i>H. Pylori</i> Activity and Immunomodulatory Effects. [PDF]
Lu J +5 more
europepmc +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Altered phenotype and gene expression of regulatory T cells (Tregs) in children with Autism, and the relationship with comorbid gastrointestinal symptoms. [PDF]
Moreno RJ, Rose D, Ashwood P.
europepmc +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula +10 more
wiley +1 more source
Role of CD25 on resting Treg immune cell in mediating the effect of stearate biosynthesis microbiome pathway on lung adenocarcinoma. [PDF]
Yang L +5 more
europepmc +1 more source

