Results 261 to 270 of about 152,273 (295)
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GITRL-mediated costimulation in CD25−conventional and CD25+ regulatory CD4 T cells (88.16)
The Journal of Immunology, 2007Abstract We previously reported that GITR acts as a costimulatory molecule in both CD25− CD4+ conventional and CD25+ CD4+ Treg cells using agonistic anti-GITR mAb (DTA-1) (J. Immunol. 2004, 172:7306). However, CD4 T cell responses by the binding of natural ligand, GITRL and the physiological importance of GITR-GITRL pathway have not been
Hanna Igarashi +7 more
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Role of CD25+ and CD25-T cells in acute HIV infection in vitro.
The Journal of Immunology, 1993Abstract T cell activation plays a major role in the ability of the HIV to remain latent or establish a productive infection. The alpha-chain of the IL-2R (CD25, Tac, p55) is expressed on activated but not resting T cells and therefore represents an ideal marker to distinguish activated from resting T cells.
O, Ramilo +3 more
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Dexamethasone, but not meloxicam, suppresses proliferation of bovine CD25+CD4+ and CD25-CD4+ T cells
Polish Journal of Veterinary Sciences, 2013Abstract Recently, we found that dexamethasone caused a depletion of CD25-CD4+ T cells, but it increased the number of CD25highCD4+ and CD25lowCD4+ T cells. We also determined meloxicam-induced increase in the number of CD25highCD4+ T cells. In view of this, and taking into consideration the latest reports indicating that meloxicam shows an anti ...
T, Maślanka, J J, Jaroszewski
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Anti-CD25 Immunotherapy: Regulating the Regulators
Science Translational Medicine, 2012Innate immunity, adaptive immunity, and antigen presentation collaborate to effect monoclonal antibody therapy in multiple sclerosis.
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CD25+ regulatory T cells and tumor immunity
Immunology Letters, 2003Tumor cells express a range of antigens including self-antigens (those whose expression is shared by normal host tissue) and non-self antigens (such as those that arise as a result of mutations in normal cellular genes or in the case of some tumors, viral antigens).
Emma, Jones +3 more
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Severe Dry Eye in CD25 Deficiency Syndrome
Eye & Contact Lens: Science & Clinical Practice, 2018Abstract: CD25 deficiency (Interleukin-2 receptor alpha deficiency) is a rare subtype of combined B- and T-cell immunodeficiency. Recurrent infections and lymphocyte infiltration of multiple tissues are the main clinical presentations. Only four patients have been reported in whom ophthalmological findings were not described. In this article,
Zeynep, Baş +2 more
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Molecular cloning and characterization of Duck CD25
Veterinary Immunology and Immunopathology, 2007The IL-2Ralpha chain (CD25, Tac) is an essential component of high affinity IL-2Rs, playing critical role for the immune specificity of antigen-activated T-cell clonal expansion. Up to now, no duck cytokine receptor has been described. Here, the cDNA segment of a duck cytokine receptor (duCD25), encoding a 226 aa precursor protein with a 20 aa signal ...
Jinyong, Wang +7 more
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A7.03 Il-33 inhibits experimental arthritis through CD25+ and CD25- regulatory T cells activation
Annals of the Rheumatic Diseases, 2016Background and objectives Interleukin (IL)-33 is a new member of the IL-1 family that exerts pleiotropic activities in innate and adaptive immunity. Some evidence also suggest that the IL-33/ST2 (IL-33 receptor) axis is strongly involved in the pathophysiology of rheumatoid arthritis (RA).
J Biton +4 more
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2008
CD4+/CD25+ T-regulatory cells are a suppressive subpopulation of lymphocytes that play a key role in auto-tolerance development. T-regulatory cells in cancer patients can inhibit proliferation and killer activity of cytotoxic lymphocytes and suppress anti-tumor immune response. T-suppressor number increases with the long-term cultivation of lymphocytes
Irina Zh. Shubina +2 more
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CD4+/CD25+ T-regulatory cells are a suppressive subpopulation of lymphocytes that play a key role in auto-tolerance development. T-regulatory cells in cancer patients can inhibit proliferation and killer activity of cytotoxic lymphocytes and suppress anti-tumor immune response. T-suppressor number increases with the long-term cultivation of lymphocytes
Irina Zh. Shubina +2 more
openaire +1 more source