Results 241 to 250 of about 152,273 (295)

A CD25-chemokine receptor complex initiates noncanonical IL-2 signaling. [PDF]

J Biol Chem
Lee HS, Kim SHJ, Aceil J, Meecham A, Gingras A, Ley K, Spangler JB, Ginsberg MH.   +7 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, Volume 13, Issue 24, 27 April 2026.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source

Oral tolerogenic vaccine combined with gastrin restores immune tolerance and beta-cell function in NOD mice with Type 1 diabetes. [PDF]

Front Immunol
Cobb J, Rawson J, Gonzalez N, Kandeel F, Husseiny MI.   +4 more
europepmc   +1 more source

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

Advanced Science, Volume 13, Issue 22, 17 April 2026.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu, Xianlan Chen, Jin Wang, Yuhan Liu, Sidra Mustafa, Lu Diao, Rongrong Zhao, Haiyang Chi, Kang Hu, Jiashan Zhu, Jun Zhao, Mi Liu   +11 more
wiley   +1 more source

Combined CD25-targeted near infrared photoimmunotherapy (NIR-PIT) and intratumor IL-15 enhance the effectiveness of anti-PD-1 immunotherapy. [PDF]

Cancer Immunol Immunother
Kano M, Furusawa A, Fukushima H, Takao S, Okuyama S, Yamamoto H, Suzuki M, Kano M, Kitamura K, Choyke PL, Kobayashi H.   +10 more
europepmc   +1 more source

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang, Mingjie Kuang, Jiacheng Shi, Ruiyan Li, Yuhan Zhang, Xinting Liu, Runtan Li, Yong Kang, Bin Yao, Shuquan Zhang, Xiaoyuan Ji   +10 more
wiley   +1 more source

Dysregulation of homeostatic cytokine receptors drives prolonged T cell activation following acute SARS-CoV-2 infection in humans. [PDF]

Nat Commun
Ceglarek L, Taeschler P, Inci A, Zurbuchen Y, Adamo S, Cervia-Hasler C, Raeber ME, Boyman O.   +7 more
europepmc   +1 more source

Rapamycin-modified novel tolerogenic dendritic cells induce liver graft tolerance through MHC-II+CD8+ regulatory T cells. [PDF]

Hepatol Commun
Zhou L, Zhao Y, Wang J, Chen Q, Jia YN, Pan LC, Wang HX, Yang HW, He Q, Li XL, Lang R, Du GS.   +11 more
europepmc   +1 more source

Optimising Recovery of Hepatic Regulatory T Cells: A Practical Guide Using ARTC2 Blockade. [PDF]

Eur J Immunol
Abbott C, Mouro V, Perucchini C, Vespari C, Iannacone M.   +4 more
europepmc   +1 more source