Results 31 to 40 of about 152,273 (295)

Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection [PDF]

, 2017
Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal epithelium from where they are transported to the mesenteric lymph nodes (MLNs) within migrating
A Perez-Lopez, A Srinivasan, AG Peniche, AL John St, AM Race, AS Attia, B Dugas, B Flatley, B García, BD Corbin, C Otsubo, C O’Mahony, CS Macedo de, E-H Hong, F Hacini-Rachinel, FM Goñi, G Robichaud, G Walzl, GM Fraser, IB Wenderska, J Bene, J Hess, JD Turner, JM Ertelt, JM Rutkowsky, K Schwamborn, KA Oswald-Richter, KHG Mills, KKW To, KL O’Hagan, KSH Beckham, M Barthel, M Gaya, MA Jepson, MC Mutomba, MI Hood, MP Fink, N Desbenoit, O Klein, P Mastroeni, PL Chen, R Daniels, R Rosales-Reyes, RJA Goodwin, S Gravius, S Létourneau, S Pie, S Voedisch, T Goto, T Liu, T Okada, TG Glaros, UT Nguyen, VD Peltekova, X Liu, Y Li, Y Souwer, YR Carrasco   +57 more
core   +1 more source

Influence of tumors on protective anti-tumor immunity and the effects of irradiation [PDF]

, 2013
Innate and adaptive immunity play important roles in the development and progression of cancer and it is becoming apparent that tumours can influence the induction of potentially protective responses in a number of ways.
Alan Graham Pockley, Gabriele eMulthoff, Gabriele eMulthoff, Gemma Ann Foulds, Gemma Ann Foulds, Jürgen eRadons, Mira eKreuzer   +6 more
core   +2 more sources

Platelet Factor 4 Differentially Modulates CD4+CD25+ (Regulatory) versus CD4+CD25− (Nonregulatory) T Cells [PDF]

The Journal of Immunology, 2005
AbstractActive suppression mediated by CD4+CD25+ T regulatory (Tr) cells plays an important role in the down-regulation of T cell responses to both foreign and self-Ags. Platelet factor 4 (PF4), a platelet-derived CXC chemokine, has been shown to strongly inhibit T cell proliferation as well as IFN-γ and IL-2 release by isolated T cells. In this report
Chao Yan, Liu, Manuela, Battaglia, Seon Ho, Lee, Qi-Hong, Sun, Richard H, Aster, Gian Paolo, Visentin   +5 more
openaire   +2 more sources

The type of responder T-cell has a significant impact in a human in vitro suppression assay. [PDF]

PLoS ONE, 2010
In type 1 diabetes (T1D), a prototypic autoimmune disease, effector T cells destroy beta cells. Normally, CD4(+)CD25(+high), or natural regulatory T cells (Tregs), counter this assault.
Srikanta Jana, Hope Campbell, Jeffrey Woodliff, Jill Waukau, Parthav Jailwala, Jugal Ghorai, Soumitra Ghosh, Sanja Glisic   +7 more
doaj   +1 more source

Regulatory immune cells in transplantation [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Bushell, Andrew, Hester, Joanna, Wood, Kathryn J   +2 more
core   +1 more source

MARCH1 protects the lipid raft and tetraspanin web from MHCII proteotoxicity in dendritic cells [PDF]

, 2018
Dendritic cells (DCs) produce major histocompatibility complex II (MHCII) in large amounts to function as professional antigen presenting cells. Paradoxically, DCs also ubiquitinate and degrade MHCII in a constitutive manner.
Anderson, Anderson, Baravalle, Bartee, Berditchevski, Björkholm, Charrin, Charrin, Chen, Chyi-Song Hsieh, Corcoran, De Gassart, Giudicelli, Golshayan, Hanada, Haribhai, Heather Pua, Hiltbold, Hoffmann, Hsieh, Hsieh, Jaehak Oh, Jeoung-Sook Shin, Justin S.A. Perry, Kato, Klein, Kondoh, Kropshofer, Kurts, Lehner, Matsuki, Metz, Mottet, Nicole Irgens-Möller, Odintsova, Oh, Oh, Ohmura-Hoshino, Perry, Powrie, Roy, Sachl, Sala-Valdés, Satoshi Ishido, Sharom, Shin, Simons, Stritesky, Unternaehrer, van Niel, Veerapathran, Walseng, Yamaji, Yamazaki, Zimmerman   +54 more
core   +2 more sources

Causal relationships between CD25 on immune cells and hip osteoarthritis

Frontiers in Immunology, 2023
ObjectivesPrevious research has indicated a potential association between immune factors and osteoarthritis (OA), but the causal relationship between CD25 expression on immune cells and hip OA remains enigmatic.
Hao Luo, Hao Luo, Yong Zhu, Bin Guo, Zhe Ruan, Zhi Liu, Zhihua Fan, Shushan Zhao, Shushan Zhao   +8 more
doaj   +1 more source

Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established.
Parnian Navabi, Mohamad Reza Ganjalikhany, Sepideh Jafari, Moein Dehbashi, Mazdak Ganjalikhani-Hakemi   +4 more
doaj   +1 more source

CD4⁺CD25⁺ Cells Are Essential for Maintaining Immune Tolerance in Chickens Inoculated with Bovine Serum Albumin at the Late Stage of Embryonic Development

Veterinary Sciences, 2020
In this study, the role of chicken CD4+CD25+ cells during induced immunotolerance was tested. Properties of chicken CD4+CD25+ cells sorted by flow cytometry were analyzed.
Xiaoxue Yu, Yufang Meng, Pengyu Pan, Liuan Li, Lei Rui, Zandong Li   +5 more
doaj   +1 more source

Partial regulatory T cell depletion prior to schistosomiasis vaccination does not enhance the protection. [PDF]

PLoS ONE, 2012
CD4(+)CD25(+) regulatory T cells (Tregs) do not only influence self-antigen specific immune responses, but also dampen the protective effect induced by a number of vaccines.
Xuefeng Wang, Fan Liu, Sha Zhou, Zhipeng Xu, Jason Hoellwarth, Xiaojun Chen, Lei He, Rongbo Zhang, Feng Liu, Jun Wang, Chuan Su   +10 more
doaj   +1 more source