Results 221 to 230 of about 107,086 (298)

CD151 identifies a cytotoxic CD4 T cell population enriched in people with HIV that later develop cancer. [PDF]

J Immunol
Perez M, Zhu F, Carlin E, Greer BD, Schroeder A, Lowman KE, Opsteen S, Fram T, Tidwell C, Duverger A, Wagner F, Moylan DC, Prichard L, Kobie J, Heath SL, Goepfert PA, Hu H, Sabbaj S, Kutsch O, Erdmann NB.   +19 more
europepmc   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

The Impact of Severe Albuminuria on the Proinflammatory Monocyte Subset CD14++CD16+ and Antigen-Specific Immune Responses. [PDF]

Int J Mol Sci
Luna Sandoval H, Ulrich C, Markau S, Girndt M.   +3 more
europepmc   +1 more source

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

HIV Medicine, EarlyView.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart, R. Palich, M. Veyri, S. Bregigeon‐Ronot, M.‐C. Picot, C. Vidal, L. Galicier, S. Choquet, J.‐P. Spano, M.‐A. Valantin, A. Makinson   +10 more
wiley   +1 more source

MiR-139 modulates CD8⁺ T cells exhaustion by targeting CD28 in breast cancer. [PDF]

iScience
Chen J, Zhang H, Lv Y, Li X, Hu M.
europepmc   +1 more source

ICSH Guidance on Bone Marrow Examination and Reporting

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology   +6 more
wiley   +1 more source

The CRAC channel inhibitor Auxora reprograms pathogenic alveolar macrophage-T cell circuits in viral pneumonia. [PDF]

J Clin Invest
Casalino-Matsuda SM, Guggilla V, Gao CA, DeMeulenaere KE, Cusick L, Fenske SW, Yu Z, Lu Z, Swaminathan S, Grant RA, Schleck MJ, Prakriya M, Hebbar S, Stauderman K, Donnelly HK, Pickens CI, Morales-Nebreda L, Wunderink RG, Misharin AV, Singer BD, Budinger GRS.   +20 more
europepmc   +1 more source

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Mendelian Randomization and Experimental Validation Identify Key Immune Signatures in Bullous Pemphigoid. [PDF]

Clin Cosmet Investig Dermatol
Wang Z, Cui H, Meng L, Yang X, Ye J.
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source