Mechanosensing by T cells promotes a tissue-resident memory transcriptional program. [PDF]
Postat J +21 more
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CAR T before the storm: early consolidation in B-ALL. [PDF]
Shouval R, Muffly L.
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Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis. [PDF]
Georgiev P +14 more
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Comprehensive immune profiling of human peripheral blood mononuclear cells using two complementary spectral flow cytometry panels encompassing 60 unique markers. [PDF]
Rietdijk MH +5 more
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The HMG-CoA Reductase Inhibitor Fluvastatin Promotes Th2-Skewed Immune Responses by Modulating Dendritic Cell Differentiation. [PDF]
Ishikawa S +7 more
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Peripheral CD8+ T Cell Dynamics and Clinical Outcomes in Metastatic Non-Small Cell Lung Cancer Following Bronchoscopic Cryotherapy and Pembrolizumab-Based Therapy. [PDF]
Vasiliauskas G +5 more
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CD28 was identified in early 1980s by Martin and colleagues by monoclonal antibodies recognizing a 44 kDa protein on the surface of human T lymphocytes (Martin et al. 1980). Further experiments from Gmunder and Lessener evidenced the crucial role of this molecule in costimulating T cell responses by synergizing with PHA in inducing T cell proliferation
luigi racioppi +13 more
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CD28/B7 Costimulation: A Review
Critical Reviews in Immunology, 1998The current model of T cell activation requires two signals. The first signal is specific, requiring T cell receptor recognition and binding to MHC/Antigen presented by an antigen-presenting cell. The second signal is nonspecific, resulting from the binding of B7 ligand on the antigen-presenting cell with its receptor, CD28, on the T cell.
Vijay Kuchroo +2 more
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