The recombinant pseudorabies virus expressing African swine fever virus CD2v protein is safe and effective in mice [PDF]
Virology Journal, 2020 Background African swine fever (ASF) leads to high mortality in domestic pigs and wild boar and is caused by the African swine fever virus (ASFV). Currently, no vaccine is commercially available for prevention, and the epidemic is still spreading.
Zhihua Feng +6 more
doaj +5 more sources
In silico prediction of B- and T-cell epitopes in the CD2v protein of african swine fever virus (African swine fever virus, Asfivirus, Asfarviridae) [PDF]
Вопросы вирусологии, 2020 Introduction. African swine fever virus (ASF) is a large DNA virus that is the only member of the Asfarviridae family. The spread of the ASF virus in the territory of the Russian Federation, Eastern Europe and China indicates the ineffectiveness of ...
Ksenia A. Mima +4 more
doaj +6 more sources
From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes [PDF]
mBioAfrican swine fever virus (ASFV) is a high-consequence pathogen posing a substantial threat to global food security. This large DNA virus encodes more than 150 open reading frames, many of which are uncharacterized.
Ana Luisa Reis +10 more
doaj +4 more sources
Screening of host proteins interacting with the African swine fever virus outer membrane protein CD2v [PDF]
Frontiers in MicrobiologyBackgroundThe African swine fever virus (ASFV) is a highly pathogenic double-stranded DNA virus that poses a significant threat to the global swine industry.
Xiong-nan Chen +32 more
doaj +3 more sources
Expression of extracellular domain of ASFV CD2v protein in mammalian cells and identification of B cell epitopes. [PDF]
Virus Res, 2023 African swine fever virus (ASFV), a highly pathogenic large DNA virus, is the cause of African swine fever worldwide. The ASFV virulence gene EP402R encodes CD2v, a structural protein that plays an important role in the ASFV infection process. In this study, a CHO-S cell line stably expressing the extracellular region of CD2v was generated and ...
Liu H +8 more
europepmc +3 more sources
Frontiers in Microbiology, 2022 African swine fever virus (ASFV), a DNA double-stranded virus with high infectivity and mortality, causing a devastating blow to the pig industry and the world economy. The CD2v protein is an essential immunoprotective protein of ASFV.
Siyuan Liu +16 more
doaj +3 more sources
SEROTYPE-SPECIFIC AND HAEMADSORPTION PROTEIN OF THE AFRICAN SWINE FEVER VIRUS [PDF]
Slovenian Veterinary Research, 2018 This review presents comparative results of simultaneously conducted studies on proteins responsible for the haemadsorption and serotype-specific properties of African swine fever virus (ASFV).
Alexey D. Sereda +3 more
doaj +3 more sources
The ASFV CD2v protein inhibits apoptosis by inducing proteasomal degradation of BimEL via activation of the TPL2-MEK-ERK signaling pathway [PDF]
Journal of VirologyAfrican swine fever virus (ASFV) employs sophisticated regulatory strategies to manipulate host cell apoptosis, a process critical for its pathogenesis and immune evasion; however, the mechanisms underlying this process remain incompletely understood ...
Jianyu Zeng +15 more
doaj +2 more sources
Identification of T-cell epitopes in African swine fever virus CD2v and C-type lectin proteins. [PDF]
Journal of General Virology, 2019 African swine fever (ASF) is an emerging disease threat for the swine industry worldwide. No ASF vaccine is available, and progress is hindered by lack of knowledge concerning the extent of ASF virus (ASFV) strain diversity and the viral antigens ...
Burmakina, Galina +6 more
core +4 more sources
浙江大学学报. 农业与生命科学版, 2023 The aim of this study was to systematically investigate the differences in the soluble expression level of the African swine fever virus (ASFV) CD2v protein by different prokaryotic expression vectors, and the immunoreactivities of the inclusion body and
FENG Mengke +5 more
doaj +2 more sources