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Development and Application of Mouse-Derived CD2v Monoclonal Antibodies Against African Swine Fever Virus from Single B Cells [PDF]

Viruses
African swine fever (ASF) is a highly pathogenic and hemorrhagic swine infectious disease caused by the African swine fever virus (ASFV). It encodes over 150 proteins, among which the CD2v protein plays multiple roles throughout the infection process ...
Litao Yu, Fangtao Li, Xingqi Zou, Lu Xu, Junjie Zhao, Yan Li, Guorui Peng, Yingju Xia, Qizu Zhao, Yuanyuan Zhu   +9 more
doaj   +2 more sources

An Update on African Swine Fever Virology [PDF]

Viruses, 2019
Animal diseases constitute a continuing threat to animal health, food safety, national economy, and the environment. Among those, African swine fever (ASF) is one of the most devastating viruses affecting pigs and wild suids due to the lack of vaccine or
Axel Karger, Daniel Pérez-Núñez, Jesús Urquiza, Patricia Hinojar, Covadonga Alonso, Ferdinando B. Freitas, Yolanda Revilla, Marie-Frédérique Le Potier, Maria Montoya   +8 more
doaj   +3 more sources

ASF virus replication features in the presence of recombinant proteins CD2v, pX69R and pE248R

Вопросы вирусологии, 2019
Introduction. African swine fever (ASF), sever hemorrhagic disease of swine caused by a large DNA virus of the Asfaviridae family. Since there are no effective and safe vaccines against ASF yet, it is urgent to study the functions of its proteins, which ...
A. Mazloum, I. U. Zhukov, E. B. Aronova, A. S. Igolkin, N. N. Vlasova   +4 more
doaj   +4 more sources

Molecular Characterization of African Swine Fever Viruses Circulating in Can Tho City, Vietnam

Veterinary Medicine International, 2023
African swine fever (ASF) is a highly contagious and deadly viral disease in domestic and feral pigs. Since 2018, the disease has spread and caused large socioeconomic consequences to the pig industry in several Asian countries including China, Vietnam ...
Nguyen Duc Hien, Le Trung Hoang, To My Quyen, Nguyen Phuc Khanh, Lam Thanh Nguyen   +4 more
doaj   +2 more sources

Correction: Jiang et al. Identification of Two Novel Linear B Cell Epitopes on the CD2v Protein of African Swine Fever Virus Using Monoclonal Antibodies. Viruses 2023, 15, 131 [PDF]

Viruses
In the original publication [...]
Wenting Jiang, Dawei Jiang, Lu Li, Jiabin Wang, Panpan Wang, Xuejian Shi, Qi Zhao, Boyuan Liu, Pengchao Ji, Gaiping Zhang   +9 more
doaj   +2 more sources

Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface [PDF]

Open Veterinary Journal
Background: African swine fever (ASF) continues to hamper pork production worldwide. In addition to vaccines, there is a need to develop curative therapeutics, such as highly-specific antibodies or nanobodies, against immunogenic proteins with important
Albert Neil Gura Dulay, Richelle Mae Evasco Padilla, Nyzar Mabeth Obenio Odchimar, Fredmoore Legaspi Orosco   +3 more
doaj   +2 more sources

A triple protein-based ELISA for differential detection of ASFV antibodies [PDF]

Frontiers in Veterinary Science
African swine fever (ASF) caused by the ASF virus (ASFV) is a severe and highly contagious viral disease that poses a significant threat to the global pig industry.
Shuai Zhang, Yuzhu Zuo, Wenyuan Gu, Yunhuan Zhao, Ying Liu, Jinghui Fan, Jinghui Fan   +6 more
doaj   +2 more sources

A synthetic genomics-based African swine fever virus engineering platform. [PDF]

Sci Adv
African swine fever (ASF) is a deadly viral disease in domestic pigs that has a large global economic impact for the swine industry. It is present in Africa, Europe, Asia, and in the Caribbean island of Hispaniola.
Fuchs W, Assad-Garcia N, Abkallo HM, Xue Y, Oldfield LM, Fedorova N, Hübner A, Kabuuka T, Pannhorst K, Höper D, Nene V, Gonzalez-Juarbe N, Steinaa L, Vashee S.   +13 more
europepmc   +3 more sources

Nanobodies against African swine fever virus p72 and CD2v proteins as reagents for developing two cELISAs to detect viral antibodies. [PDF]

Virol Sin
African swine fever virus (ASFV) poses a significant threat to the global swine industry. Currently, there are no effective vaccines or treatments available to combat ASFV infection in pigs. The primary means of controlling the spread of the disease is through rapid detection and subsequent elimination of infected pig.
Zhu J, Liu Q, Li L, Zhang R, Chang Y, Zhao J, Liu S, Zhao X, Chen X, Sun Y, Zhao Q.   +10 more
europepmc   +3 more sources

Construction and Evaluation of Quadruple-Gene-Deleted Pseudorabies Virus Platforms for ASFV Antigen Delivery. [PDF]

Transbound Emerg Dis
African Swine Fever (ASF) is a highly lethal viral disease in swine. The emergence and rapid spread of African Swine Fever virus (ASFV) in China, since 2018 have caused significant economic losses to the pig farming industry. The complexity of ASFV has impeded the development of effective vaccines, and with no commercial vaccines currently available in
Li H, Guo R, Jia Y, Zhang X, Liu Z, Shi W, Hu R, Zhang Y, Nasir S, Han L, Qiu X, Wang X.   +11 more
europepmc   +2 more sources