Results 91 to 100 of about 389,148 (301)
Advanced Materials, EarlyView.The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena +10 more
wiley +1 more source
Discover OncologyPurpose The purpose of this study was to analyze the expression patterns of immune cells in renal cancer patients, including myeloid-derived suppressor cells (MDSCs), regulatory T cells (Tregs), CD3 + /CD4 + T cells, CD3 + / CD8 + T cells, and CD3- CD16 +
Yan Li +4 more
doaj +1 more source
Frontiers in Immunology, 2018 Natural killer (NK) cells play a pivotal role in the immune response against infections and malignant transformation, and adopted transfer of NK cells is thought to be a promising therapeutic approach for cancer patients.
Soo-Hyeon Lee +18 more
doaj +1 more source
, 2023 Influence of NAC in the CD3+ T cells infiltration of BC tumors. Forest plot for the different outcomes regarding CD3+ T cells infiltration before and after NAC.
María Alejandra Villota-Álava (15368651) +8 more
core +1 more source
Advanced Materials, EarlyView.Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song +8 more
wiley +1 more source
Structural model of the Extracellular Assembly of the TCR-CD3 Complex
Cell Reports, 2016 Summary Antigen recognition of peptide-major histocompatibility complexes (pMHCs) by T-cells, a key step in initiating adaptive immune responses, is performed by the T-cell receptor (TCR) bound to CD3 heterodimers.
A. Natarajan +8 more
semanticscholar +1 more source
CD3 immunofluorescence in porcine conjunctiva.
, 2020 Dotted line marks the limits of the same follicle shown in each of the panels. Dotted-dash lines mark the limit between conjunctival epithelium and stroma.
Mario Crespo-Moral (8292975) +3 more
core +1 more source
Advanced Science, EarlyView.Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin +20 more
wiley +1 more source
Generation of CD3+ thymocytes.
, 2013 (A) CD7hiCD3hi and CD7 dim CD3⁻ cells were detected at day 7. (B) By day 12 approximately 90% of all the cells generated were CD3+ thymocytes. (C) A matrix seeded with approximately 300 CD34+ cord blood derived progenitors generated about 2900 CD3+ cells
Richard Aspinall (348825) +3 more
core +1 more source
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source