Results 11 to 20 of about 280,132 (264)
CD3 receptor modulation in Jurkat leukemic cell line.
Folia Histochemica et Cytobiologica, 2004 CD3 antigen is a crucial molecule in T cell signal transduction. Although its expression on cell surface is constitutive, dynamic regulation of TCR-CD3 level is probably the most important mechanism allowing T cells to calibrate their response to ...
Jacek M Witkowski +3 more
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CD3+CD8+CD28− T Lymphocytes in Patients with Lupus Nephritis [PDF]
Journal of Immunology Research, 2016 The results of studies on the CD3+CD8+CD28- cells in SLE are inconsistent since several analyses describe CD3+CD8+CD28- as either immunosuppressive or cytotoxic.
Marcelina Żabińska +3 more
doaj +2 more sources
, 2022 INTRODUCTION: Systemic lupus erythematosus (SLE) patients have decreased natural killer (NK) cell counts. The decrease in the number of NK cells has implications for a decrease in the function of NK cells which can affect the progression of SLE disease ...
Dwi Soelistyoningsih +7 more
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The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules [PDF]
, 1992 Recent studies have demonstrated that the CD3-ζ subunit of the T cell antigen receptor (TCR) complex is involved in signal transduction. However, the function of the remaining invariant subunits, CD3-γ, -δ, and , is still poorly understood.
Wegener, Anne-Marie K. +19 more
core +1 more source
Neolymphogenesis and Immunogistogochemical Study of Lymph Nodes in Breast Cancer
Креативная хирургия и онкология, 2020 Background. Our previous studies have shown that postnatally formed lymph nodes (PNFLN) can serve as a source of biological signals activating antitumour immune reactions and suppressing the spread of metastatic malignant cells.Aim.
Sh. Kh. Gantsev +3 more
doaj +1 more source
Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)
Креативная хирургия и онкология, 2020 This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov +2 more
doaj +1 more source
Horizontal and vertical distribution of CD3+ lymphocytes in the intestine of healthy adult and neonatal dogs [PDF]
, 2017 T-lymphocytes are considered to play an essential role in the pathogenesis of inflammatory bowel disease. The goal of this study was an objective determination of the distribution of gastrointestinal CD3+ lymphocytes in a standardized dog population as a
Pfammatter, Nadia +5 more
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, 2023 In cancer research, the mechanism underlying the immune response to a tumour has been of great interest. In this study, we investigated the role of CD274 (programmed cell death-ligand 1 – PD-L1) and CD3+ tumour-infiltrating lymphocytes (TILs) in the ...
Suat Benek, Mehmet Zengin
core +1 more source
A Novel T Cell-Engaging Bispecific Antibody for Treating Mesothelin-Positive Solid Tumors
Biomolecules, 2020 As mesothelin is overexpressed in various types of cancer, it is an attractive target for therapeutic antibodies. T-cell bispecific antibodies bind to target cells and engage T cells via binding to CD3, resulting in target cell killing by T-cell ...
Aerin Yoon +8 more
doaj +1 more source
Spleenic Lymphoma and Hemoperitoneum in Jersey Bull: Clinical and Pathological Aspects
Brazilian Journal of Veterinary Pathology, 2014 Lymphoma is the most prevalent neoplasia in dairy cattle. The etiology can be viral in animals affected by bovine leukemia virus (BLV) or be classified as primary.
Paulo Henrique Sampaio +6 more
doaj +1 more source