Results 11 to 20 of about 243,350 (258)

Solitary fibrous tumor/hemangiopericytoma of the external auditory canal

open access: yesActa Oto-Laryngologica Case Reports, 2019
Introduction: Solitary fibrous tumor/hemangiopericytoma is an uncommon neoplasm that accounts for only 1–2% of all soft tissue tumors. To the best of our knowledge only three cases of this tumor have been described in the external auditory canal in the ...
Jefferson Rijo-Cedeño   +3 more
doaj   +1 more source

Evaluation of lymphocyte migration to induced paederus dermatitis: An experimental study in rats

open access: yesIndian Journal of Dermatology, 2019
Background: Paederus dermatitis (PD) is a blistering disorder that is caused by a small insect of the genus Paederus, especially Paederus fuscipes. This study aimed to investigate the reaction of the adaptive immune system regarding the recruitment of ...
Fereshteh Hosseini Valiki   +4 more
doaj   +1 more source

Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)

open access: yesКреативная хирургия и онкология, 2020
This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov   +2 more
doaj   +1 more source

A Novel T Cell-Engaging Bispecific Antibody for Treating Mesothelin-Positive Solid Tumors

open access: yesBiomolecules, 2020
As mesothelin is overexpressed in various types of cancer, it is an attractive target for therapeutic antibodies. T-cell bispecific antibodies bind to target cells and engage T cells via binding to CD3, resulting in target cell killing by T-cell ...
Aerin Yoon   +8 more
doaj   +1 more source

Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis

open access: yesAvicenna Journal of Medicine, 2014
Hepatosplenic T-cell lymphoma (HSTL) is a rare T-cell neoplasm of the lymphoid system. This type of lymphoma is characterized by sinusoidal infiltration of spleen, liver, bone marrow and lymph nodes by neoplastic lymphocytes.
Ali M Gabali   +4 more
doaj   +1 more source

Correlation between peripheral blood lymphocyte subpopulations and primary systemic lupus erythematosus

open access: yesOpen Life Sciences, 2022
This study explored the correlation between peripheral blood CD3+, CD3+/CD4+, CD3+/CD8+, CD4+/CD8+, CD3−/CD16+ CD56+, and CD3−CD19+ and disease activity of different subtypes of systemic lupus erythematosus (SLE). The percentages of CD3+, CD3+/CD4+, CD3+/
Feng Yan   +3 more
doaj   +1 more source

Immunological cluster complexes in kidney transplantation

open access: yesМедицинская иммунология, 2022
Laboratory tests are significant for the detection of immunopathological disorders in kidney transplantation. As a rule, the choice of tests is carried out individually and is based on the clinical characteristics and the presumptive diagnosis.
S. V. Zybleva, S. L. Zyblev
doaj   +1 more source

Acquired aberrant partial CD3 expression in recurrent Epstein-Barr virus–negative solitary plasmacytoma of tonsil [PDF]

open access: yesJournal of Pathology and Translational Medicine
The aberrant expression of specific T-cell maker CD3 in B-cell neoplasms can be a potential diagnostic pitfall leading to a misclassification of cell lineage.
Chenchen Niu   +5 more
doaj   +1 more source

Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody

open access: yesOncoImmunology, 2017
T-cell-based therapies have emerged as one of the most clinically effective ways to target solid and non-solid tumors. HER2 is responsible for the oncogenesis and treatment resistance of several human solid tumors.
Andres Lopez-Albaitero   +10 more
doaj   +1 more source

A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors

open access: yesOncoImmunology, 2018
We assessed the tolerability and antitumor activity of solitomab, a bispecific T-cell engager (BiTE®) antibody construct targeting epithelial cell adhesion molecule (EpCAM).
Maxim Kebenko   +16 more
doaj   +1 more source

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