Results 21 to 30 of about 243,350 (258)

The pathophysiologic significance of lymphocyte subset determination in children with infectious mononucleosis, mycoplasma pneumonia and Henoch–Schönlein purpura

open access: yesBMC Pediatrics, 2022
Objective This study aimed to explore lymphocyte subset determinations as an aid to understanding the pathophysiology of infectious mononucleosis (IM), pneumonia due to mycoplasma infection (P-MI) and Henoch–Schönlein purpura in children.
Liang Zhao   +3 more
doaj   +1 more source

Fishmeal substitution for Arthrospira platensis in juvenile mullet (Mugil liza) and its effects on growth and non-specific immune parameters

open access: yesRevista Colombiana de Ciencias Pecuarias, 2019
Background: Cyanobacterium Athrospira platensis (Spirulina) is a potential fishmeal (FM) substitute in fish diets because of its high protein content, antioxidant and immunostimulant properties.
Victor Torres Rosas   +3 more
doaj   +1 more source

Aberrant Alteration of Circulating Lymphocyte Subsets in Small Cell Lung Cancer Patients Treated with Radiotherapy

open access: yesTechnology in Cancer Research & Treatment, 2021
Purpose: The role of different circulating lymphocyte subsets, as well as their correlation with clinical characteristics of small cell lung cancer patients have not yet been fully understood.
Hui Li MD   +5 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean   +7 more
wiley   +1 more source

CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS

open access: yesМедицинская иммунология, 2014
. We have studied effects of UV irradiation (240-390 nm) at a dose range of 151 to 1359 J/m2 upon expression levels of different surface markers (CD2, CD11a, CD3, CD4, CD8) of human blood T lymphocytes by means of laser flow cytofluorimetry.
V. G. Artuykhov   +3 more
doaj   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley   +6 more
wiley   +1 more source

Residual Bone Marrow T & NK-Cells at Diagnosis in Pediatric Pre-B-ALL: A Case–Control Study

open access: yesInternational Journal of General Medicine, 2022
Dalia Mahmoud Eldewi,1 Hanan A El‑Hagrasy,1 Rasha Mahmoud Gouda,2 Mohammed Abd El Malik Hassan,3 Shimaa Moustafa Kamel,2 Naglaa F Abd El Haliem,4 Haneya AA Anani4 1Department of Clinical Pathology - Faculty of Medicine (For Girls), Al‑Azhar University ...
Eldewi DM   +6 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

CD8+ T lymphocyte is a main source of interferon-gamma production in Takayasu’s arteritis

open access: yesScientific Reports, 2021
Interferon-gamma (IFN-γ) is a cytokine involved in the pathogenesis of Takayasu’s arteritis (TAK). However, the source of IFN-γ in TAK patients is not fully clear. We aimed to investigate the source of IFN-γ in TAK. 60 TAK patients and 35 health controls
Yan-Long Ren   +10 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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