Results 21 to 30 of about 280,132 (264)

Solitary fibrous tumor/hemangiopericytoma of the external auditory canal

Acta Oto-Laryngologica Case Reports, 2019
Introduction: Solitary fibrous tumor/hemangiopericytoma is an uncommon neoplasm that accounts for only 1–2% of all soft tissue tumors. To the best of our knowledge only three cases of this tumor have been described in the external auditory canal in the ...
Jefferson Rijo-Cedeño, Luz Martín-Figueiro, Harold Tavárez, Rafael Ramírez-Camacho   +3 more
doaj   +1 more source

T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase [PDF]

, 2001
After stimulation of the T cell receptor (TCR), the tyrosine residues 292 and 315 in interdomain B of the protein tyrosine kinase ZAP-70 become phosphorylated and plausibly function as docking sites for Cbl and Vav1, respectively. The two latter proteins
Magnan, A, Anne Gillet, Arrieumerlou, C, Antoine Magnan, Boyer, C, Malissen, Bernard, Vincenzo Di Bartolo, Mireille Richelme, Marie Malissen, Lin, YL, Gillet, A., Roure, A, Mura, A. M., Boyer, C., Malissen, B, Arrieumerlou, C., Malissen, M., Malissen, M, Roure, A., Richelme, M, Acuto, O, Lin, Y. L., Bernard Malissen, Claude Boyer, Malissen, B., Di Bartolo, V, Cécile Arrieumerlou, Yea-Lih Lin, Agnès Roure, Oreste Acuto, Mura, AM, Acuto, O., Richelme, M., Acuto, Oreste, Di Bartolo, V., Anne-Marie Mura, Gillet, A, Boyer, Claudine, Magnan, A.   +38 more
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Correlation between peripheral blood lymphocyte subpopulations and primary systemic lupus erythematosus

Open Life Sciences, 2022
This study explored the correlation between peripheral blood CD3＋, CD3＋/CD4＋, CD3+/CD8+, CD4＋/CD8＋, CD3−/CD16+ CD56+, and CD3−CD19+ and disease activity of different subtypes of systemic lupus erythematosus (SLE). The percentages of CD3+, CD3+/CD4+, CD3+/
Feng Yan, Li Zhijun, Xie Changhao, Lu Fanglin   +3 more
doaj   +1 more source

Immunological cluster complexes in kidney transplantation

Медицинская иммунология, 2022
Laboratory tests are significant for the detection of immunopathological disorders in kidney transplantation. As a rule, the choice of tests is carried out individually and is based on the clinical characteristics and the presumptive diagnosis.
S. V. Zybleva, S. L. Zyblev
doaj   +1 more source

Acquired aberrant partial CD3 expression in recurrent Epstein-Barr virus–negative solitary plasmacytoma of tonsil [PDF]

Journal of Pathology and Translational Medicine
The aberrant expression of specific T-cell maker CD3 in B-cell neoplasms can be a potential diagnostic pitfall leading to a misclassification of cell lineage.
Chenchen Niu, Dong Ren, Truc Tran, Ashley Gamayo, Sherif Rezk, Xiaohui Zhao   +5 more
doaj   +1 more source

Expression of CD80/MHCII, CD3 and GATA-3/CD3 in SL culture.

, 2023
Expression of CD80 in MHCII+ (CD80/MHCII) leukocytes (A), CD3 (B) and GATA-3 in TCD3+ leukocytes (GATA-3/CD3) (C). Splenic leukocytes from control (healthy dogs) and CanL (dogs naturally infected by L.
Gabriela Torres Rebech (6053297), Valéria Marçal Felix de Lima (8115269), Sidnei Ferro Costa (8115260), Marilene Oliveira dos Santos (12290053), Jaqueline Poleto Bragato (5488034), Flávia de Rezende Eugênio (8115263), Jéssica Henrique de Freitas (12290050), Paulo Sérgio Patto dos Santos (12290059), Matheus Fujimura Soares (14526507)   +8 more
core   +1 more source

Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody

OncoImmunology, 2017
T-cell-based therapies have emerged as one of the most clinically effective ways to target solid and non-solid tumors. HER2 is responsible for the oncogenesis and treatment resistance of several human solid tumors.
Andres Lopez-Albaitero, Hong Xu, Hongfen Guo, Linlin Wang, Zhihao Wu, Hoa Tran, Sarat Chandarlapaty, Maurizio Scaltriti, Yelena Janjigian, Elisa de Stanchina, Nai-Kong V. Cheung   +10 more
doaj   +1 more source

Modulating T Cell Responses by Targeting CD3

, 2023
Simple Summary CD3 complex provides the first signal sensed by the TCR of the lymphocyte to trigger its activation. Thus, it becomes a very attractive receptor to determine the fate of the immune response in different contexts from tolerance induction to
Moreno, B. (Beatriz), Villanueva-Ruiz, M.E. (María Elena), van-Santen, H.M. (Hisse M.), Meraviglia-Crivelli, D. (Daniel), Zheleva, A. (Angelina), Pastor, F. (Fernando), Barainka, M. (Martin), Menon, A.P. (Ashwathi Puravankara), Nonatelli, F. (Francesca)   +8 more
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A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors

OncoImmunology, 2018
We assessed the tolerability and antitumor activity of solitomab, a bispecific T-cell engager (BiTE®) antibody construct targeting epithelial cell adhesion molecule (EpCAM).
Maxim Kebenko, Marie-Elisabeth Goebeler, Martin Wolf, Annette Hasenburg, Ruth Seggewiss-Bernhardt, Barbara Ritter, Beate Rautenberg, Djordje Atanackovic, Andrea Kratzer, James B. Rottman, Matthias Friedrich, Eva Vieser, Stefanie Elm, Ingrid Patzak, Dorothea Wessiepe, Sabine Stienen, Walter Fiedler   +16 more
doaj   +1 more source

CD3-positive T-lymphocytes and CD68-KP1-positive cells in the atrial myocardium.

, 2017
Sections of atrial myocardium from patients with atrial fibrillation showing a result of immunoperoxidase reaction for CD3 and CD68-KP1. A) CD3-positive T-lymphocytes localized among atrial cardiomyocytes and in the interstitial spaces (arrowheads ...
Jan Pirk (753952), Tomáš Kučera (807898), Mária Ďurišová (3772792), Vojtěch Melenovský (753950), Martin Bláha (753949), Natalia Smorodinova (753947), Karolína Rozsívalová (3772786), Jaromír Přidal (3772789), Josef Kautzner (753953)   +8 more
core   +1 more source