Results 21 to 30 of about 304,036 (298)
Tumor Infiltrating Neutrophils Are Enriched in Basal-Type Urothelial Bladder Cancer
Background: Urothelial bladder cancers (UBCs) are distinct in two main molecular subtypes, namely basal and luminal type. Subtypes are also diverse in term of immune contexture, providing a rationale for patient selection to immunotherapy.
Giulio Eugenio Mandelli +14 more
doaj +1 more source
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules [PDF]
Recent studies have demonstrated that the CD3-ζ subunit of the T cell antigen receptor (TCR) complex is involved in signal transduction. However, the function of the remaining invariant subunits, CD3-γ, -δ, and , is still poorly understood.
Wegener, Anne-Marie K. +19 more
core +1 more source
Spleenic Lymphoma and Hemoperitoneum in Jersey Bull: Clinical and Pathological Aspects
Lymphoma is the most prevalent neoplasia in dairy cattle. The etiology can be viral in animals affected by bovine leukemia virus (BLV) or be classified as primary.
Paulo Henrique Sampaio +6 more
doaj +1 more source
Solitary fibrous tumor/hemangiopericytoma of the external auditory canal
Introduction: Solitary fibrous tumor/hemangiopericytoma is an uncommon neoplasm that accounts for only 1–2% of all soft tissue tumors. To the best of our knowledge only three cases of this tumor have been described in the external auditory canal in the ...
Jefferson Rijo-Cedeño +3 more
doaj +1 more source
Evaluation of lymphocyte migration to induced paederus dermatitis: An experimental study in rats
Background: Paederus dermatitis (PD) is a blistering disorder that is caused by a small insect of the genus Paederus, especially Paederus fuscipes. This study aimed to investigate the reaction of the adaptive immune system regarding the recruitment of ...
Fereshteh Hosseini Valiki +4 more
doaj +1 more source
Neolymphogenesis and Immunogistogochemical Study of Lymph Nodes in Breast Cancer
Background. Our previous studies have shown that postnatally formed lymph nodes (PNFLN) can serve as a source of biological signals activating antitumour immune reactions and suppressing the spread of metastatic malignant cells.Aim.
Sh. Kh. Gantsev +3 more
doaj +1 more source
Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)
This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov +2 more
doaj +1 more source
In cancer research, the mechanism underlying the immune response to a tumour has been of great interest. In this study, we investigated the role of CD274 (programmed cell death-ligand 1 – PD-L1) and CD3+ tumour-infiltrating lymphocytes (TILs) in the ...
Suat Benek, Mehmet Zengin
core +1 more source
Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
Hepatosplenic T-cell lymphoma (HSTL) is a rare T-cell neoplasm of the lymphoid system. This type of lymphoma is characterized by sinusoidal infiltration of spleen, liver, bone marrow and lymph nodes by neoplastic lymphocytes.
Ali M Gabali +4 more
doaj +1 more source
A Novel T Cell-Engaging Bispecific Antibody for Treating Mesothelin-Positive Solid Tumors
As mesothelin is overexpressed in various types of cancer, it is an attractive target for therapeutic antibodies. T-cell bispecific antibodies bind to target cells and engage T cells via binding to CD3, resulting in target cell killing by T-cell ...
Aerin Yoon +8 more
doaj +1 more source

