Results 11 to 20 of about 23,011 (205)

Evaluation of CD30 expression in B ALL and its correlation with MRD(Minimum Residual Disease)

open access: yesJournal of Research in Medical Sciences, 2021
Background: This study was conducted to evaluate CD30 expression in minimum residual disease after chemotherapy in B-acute lymphoblastic leukemia (B-ALL).
Amirhossein Kazemian, Pardis Nematollahi
doaj   +1 more source

Application of PD-L1, PD-L2, CD30, CD23 and BCL-6 in Diagnosis and Prognostic Evaluation of Primary Mediastinal Large B-cell Lymphoma

open access: yesZhongliu Fangzhi Yanjiu, 2021
Objective To explore the application value of treatment-related markers PD-L1, PD-L2, CD30, CD23, BCL-2, BCL-6, MUM1 and GATA3 in the diagnosis and prognostic evaluation of primary mediastinal B-cell lymphoma(PMBL).
YUAN Ting   +4 more
doaj   +1 more source

CD30 Expression and Its Correlation with Clinicopathologic Features in Indonesian Diffuse Large B-Cell Lymphoma

open access: yesAsian Pacific Journal of Cancer Biology, 2020
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype (68.2%) of B cells Non Hodgkin Lymphoma in Indonesia. This tumor heterogeneity is characterized by a variety of clinical conditions, morphology, genetic profiles, therapeutic ...
Maria Reynelda Santoso   +3 more
doaj   +1 more source

The standardization of immunohistochemical detection and interpretation of CD30 expression in lymphomas [PDF]

open access: yesZhongguo aizheng zazhi, 2023
CD30 can be expressed in a variety of lymphoma subtypes, among which classical Hodgkin lymphoma (CHL) and anaplastic large cell lymphoma (ALCL) are the most common ones.
CD-Positive Lymphoma Pathology Expert Group
doaj   +3 more sources

Preliminary biological evaluation of 123I-labelled anti-CD30-LDM in CD30-positive lymphomas murine models

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2020
Overexpression of CD30 has been reported on the surface of some T-cell lymphomas, especially on Hodgkin’s lymphoma (HL) and anaplastic large cell lymphoma (ALCL). CD30 targeted immunotherapy has good clinical therapy response.
Jianhua Gong   +5 more
doaj   +1 more source

Memory stem T cells modified with a redesigned CD30‐chimeric antigen receptor show an enhanced antitumor effect in Hodgkin lymphoma

open access: yesClinical & Translational Immunology, 2021
Objectives Adoptive cell therapy (ACT) with mature T cells modified with a chimeric antigen receptor has demonstrated improved outcome for B‐cell malignancies.
Carmen Alvarez‐Fernández   +8 more
doaj   +1 more source

CD30+ lymphoproliferative disorders [PDF]

open access: yesHaematologica, 2010
CD30 antigen, originally identified as a cell surface marker of the malignant Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin’s lymphoma by the use of the Ki-1 monoclonal antibody, is a transmembrane glycoprotein member of the tumor necrosis factor (TNF) receptor superfamily.[1][1] In ...
de Leval, L., Gaulard, P.
openaire   +3 more sources

CD30+ Lymphoproliferative Disorders as Potential Candidates for CD30-Targeted Therapies

open access: yesArchives of Pathology & Laboratory Medicine, 2022
Context.— In the early 1980s, a monoclonal antibody termed Ki-1 was developed against a cell line derived from a patient with Hodgkin lymphoma. This antibody detected a limited number of benign activated lymphocytes in lymphoid tissue, whereas in Hodgkin lymphoma it appeared to be nearly specific for Reed ...
Roland, Schwarting   +4 more
openaire   +2 more sources

Mechanism of action and therapeutic targeting of CD30 molecule in lymphomas

open access: yesFrontiers in Oncology, 2023
At present, the treatment of lymphoma has entered the era of precision medicine, and CD30, as a transmembrane protein, has become an important marker to help the diagnosis and formulation of treatment plans for lymphomas. This protein is widely expressed
Zhaoxia Li, Wei Guo, Ou Bai
doaj   +1 more source

The expression of CD30 based on immunohistochemistry predicts inferior outcome in patients with diffuse large B-cell lymphoma. [PDF]

open access: yesPLoS ONE, 2015
The prognostic value of CD30 expression in diffuse large B-cell lymphoma (DLBCL)remains controversial. Herein, we performed this retrospective study to investigate the clinical and prognostic significance of CD30 expression in patients with DLBCL.Among ...
Xiaoxiao Hao   +7 more
doaj   +1 more source

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