Results 31 to 40 of about 23,011 (205)
Archives of Plastic Surgery, 2020 Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) has received increasing interest among plastic surgeons as a long-term complication of breast augmentation. Although the prognosis is usually good, mortality is a possible outcome.
Peera Thienpaitoon +2 more
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The Polyvalent Role of CD30 for Cancer Diagnosis and Treatment
Cells, 2023 CD30, also known as TNFRSF8 (tumor necrosis factor receptor superfamily member 8), is a protein receptor that is heavily glycosylated inside the Golgi apparatus, as well as a tumor marker that is found on the surface of specific cells in the body ...
Adrian Vasile Dumitru +6 more
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THE STANDARD OF CARE IN RELAPSED REFRACTORY CD30+ LYMPHOMA [PDF]
European Medical Journal Hematology, 2014 CD30-positive (CD30+) lymphomas are a heterogeneous group of hematological malignancies that share the same antigen. Over recent decades, advances in therapeutic management of these diseases have considerably improved clinical outcomes.
Martin Hutchings
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Brentuximab Vedotin in CD30+ Lymphomas [PDF]
Biologics in Therapy, 2013 Monoclonal antibodies (mAb) have become an effective treatment strategy for hematologic malignancies. CD30 is a rational target for therapy due to its limited expression on normal tissues and the strong and uniform expression on malignant cells in classical Hodgkin's lymphoma (cHL) and anaplastic large-cell lymphoma (ALCL). Brentuximab vedotin, an anti-
Perini, Guilherme Fleury, Pro, Barbara
openaire +2 more sources
Roles of Bcl-2 and caspase-9 and -3 in CD30-induced human eosinophil apoptosis
Journal of Microbiology, Immunology and Infection, 2017 Background/purpose: Activation of cell surface CD30 by immobilized anti-CD30 monoclonal antibodies (mAb) induces strong apoptosis in human eosinophils.
Hye Jin Lee +12 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver +25 more
wiley +1 more source
Scientific Reports, 2022 CAR T-cell therapy is well tolerated and effective in patients with Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL). However, even second- generation anti-CD30 CAR T-cells with CD28 (28z) costimulatory domains failed to achieve the ...
Shangkun Zhang +18 more
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CD30+ Lymphoproliferative Disorders of the Skin [PDF]
Hematology/Oncology Clinics of North America, 2017 Primary cutaneous CD30+ lymphoproliferative disorders encompass lymphomatoid papulosis (LyP), primary cutaneous anaplastic large cell lymphoma (pcALCL), and indeterminate cases. LyP is a benign disorder characterized by recurrent crops of red or violaceous papulonodules. Patients with LyP are at an increased risk of a secondary malignancy.
Maxwell B, Sauder +2 more
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Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
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Chinese Journal of Cancer, 2017 Background Mature T-cell and natural killer (NK)-cell lymphomas compose a heterogeneous group of non-Hodgkin lymphomas, and extranodal NK/T-cell lymphoma, nasal type (ENKTL) is an aggressive subtype with sporadic CD30 expression.
Yanfen Feng +8 more
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