CD34+ or CD34−: which is the more primitive? [PDF]
Leukemia, 2002 Remarkable progress has been achieved in the characterization and isolation of primitive hematopoietic stem cells (HSC). HSC represent a very small subset of hematopoietic cells and provide self-renewal, possess differentiation capacity and allow a constant supply of the entire hematopoietic cell spectrum.
Engelhardt, Monika +2 more
openaire +3 more sources
Journal of Education, Health and Sport, 2018 Concentrated growth factors are one of platelet-rich plasma preparations (PPP), specially prepared in medical centrifuges. Due to high concentration of blood platelets, which reveal different sorts of growth factors, CGF stimulates wound healing, reduces
Adrian Gnatek +2 more
doaj +1 more source
The effects of bone marrow stem and progenitor cell seeding on urinary bladder tissue regeneration
Scientific Reports, 2021 Complications associated with urinary bladder augmentation provide the motivation to delineate alternative bladder tissue regenerative engineering strategies.
Matthew I. Bury +8 more
doaj +1 more source
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
, 2016 Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
core +1 more source
Human CD34+ progenitor cells freshly isolated from umbilical cord blood attenuate inflammatory lung injury following LPS challenge. [PDF]
PLoS ONE, 2014 Adult stem cell-based therapy is a promising novel approach for treatment of acute lung injury. Here we investigated the therapeutic potential of freshly isolated human umbilical cord blood CD34(+) progenitor cells (fCB-CD34(+) cells) in a mouse model of
Xiaojia Huang +6 more
doaj +1 more source
Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092) [PDF]
, 2006 Background and Purpose - Loss of motor function is common after stroke and leads to significant chronic disability. Stem cells are capable of self-renewal and of differentiating into multiple cell types, including neurones, glia, and vascular cells.
Bath, Philip M.W. +7 more
core +1 more source
Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]
, 2014 Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani +59 more
core +1 more source
Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease [PDF]
, 2016 Background: Cigarette smoke induced oxidative stress has been shown to reduce silent information regulator 1 (Sirt1) levels in lung tissue from smokers and patients with COPD patients.
Akai, Masaya +11 more
core +2 more sources
Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. [PDF]
, 2018 BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection.
Abraham, David +7 more
core +3 more sources
Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]
, 1993 Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL +3 more
core +1 more source