Results 41 to 50 of about 207,267 (296)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Exploring hematopoietic stem cell population in human milk and its benefits for infants: A scoping review

open access: yesAsian Pacific Journal of Reproduction
Objective: To comprehensively explore hematopoietic stem cells (HSCs) in human milk, understanding their molecular markers, isolation methods, benefits for infants, and potential medical applications.
Ghaniyyatul Khudri, Dewi Sukmawati
doaj   +1 more source

Ex vivo expansion of hematopoietic cells today [PDF]

open access: yesScripta Medica, 2011
Ex vivo expansion (amplification) of hematopoietic stem and progenitors cells is a concept aimed to resolve the problem of insufficient number of cells for engraftment and/or to accelerate hematopoietic reconstitution after transplantation.
Ivanović Zoran
doaj  

CD14+ cells from peripheral blood positively regulate hematopoietic stem and progenitor cell survival resulting in increased erythroid yield

open access: yesHaematologica, 2015
Expansion of erythroblasts from human peripheral blood mononuclear cells is 4- to 15-fold more efficient than that of CD34+ cells purified from peripheral blood mononuclear cells.
Esther Heideveld   +7 more
doaj   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

open access: yesAdvanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung   +6 more
wiley   +1 more source

Efficiency and safety of haematopoietic stem cell collection in healthy donors

open access: yesZhongguo shuxue zazhi
[Objective] To explore the key factors affecting the efficiency and safety of hematopoietic stem cell apheresis. [Methods] The clinical data of 59 healthy donors who underwent allogeneic hematopoietic stem cell donation in the First Affiliated Hospital ...
HE Rui   +5 more
doaj   +1 more source

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells. [PDF]

open access: yesPLoS ONE, 2011
In this study, we developed a methodology to improve the survival, vascular differentiation and regenerative potential of umbilical cord blood (UCB)-derived hematopoietic stem cells (CD34(+) cells), by co-culturing the stem cells in a 3D fibrin gel with ...
Dora C S Pedroso   +7 more
doaj   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang   +7 more
wiley   +1 more source

Novel functions of the CD34 family [PDF]

open access: yesJournal of Cell Science, 2008
For almost 30 years, the cell-surface protein CD34 has been widely used as a marker to assist in the identification and isolation of hematopoietic stem cells (HSCs) and progenitors in preparation for bone-marrow transplantation. In addition, it has increasingly been used as a marker to help identify other tissue-specific stem cells, including muscle ...
Julie S, Nielsen, Kelly M, McNagny
openaire   +3 more sources

Relationship between Microvessel Count and Clinicopathological Characteristics and Postoperative Survival in Patients with Pancreatic Carcinoma [PDF]

open access: yes, 2012
Background/Aims: The present study aimed to elucidate the relationship between microvessel count (MVC) according to CD34 expression and clinicopathological characteristics or prognosis in pancreatic carcinoma (PC) patients who underwent hepatectomy ...
Fukuda, Daisuke   +11 more
core   +1 more source

Home - About - Disclaimer - Privacy