Results 41 to 50 of about 275,058 (289)
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases. [PDF]
, 2016 We examined the efficiency, specificity, and mutational signatures of zinc finger nucleases (ZFNs), transcriptional activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 systems designed to
Bjurström, Carmen F +11 more
core +3 more sources
Advanced Healthcare Materials, EarlyView.Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee +9 more
wiley +1 more source
Asian Pacific Journal of ReproductionObjective: To comprehensively explore hematopoietic stem cells (HSCs) in human milk, understanding their molecular markers, isolation methods, benefits for infants, and potential medical applications.
Ghaniyyatul Khudri, Dewi Sukmawati
doaj +1 more source
Ex vivo expansion of hematopoietic cells today [PDF]
Scripta Medica, 2011 Ex vivo expansion (amplification) of hematopoietic stem and progenitors cells is a concept aimed to resolve the problem of insufficient number of cells for engraftment and/or to accelerate hematopoietic reconstitution after transplantation.
Ivanović Zoran
doaj
Isolation and culture of vascular wall-resident cd34+ stem/progenitor cells
Cardiology Plus, 2019 Objective: The aim of this study is to observe the maintenance of stem cell properties of purified CD34-positive cells in vessel walls during in vitro expansion.
Yan Wu +3 more
doaj +1 more source
Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells [PDF]
, 2001 The inducible costimulator receptor (ICOS) is a third member of the CD28 receptor family that regulates T cell activation and function. ICOS binds to a newly identified ligand on antigen presenting cells different from the CD152 ligands CD80 and CD86. We
Aicher, A +9 more
core
Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration. [PDF]
, 2016 PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human
Annett, Geralyn +10 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source
Efficiency and safety of haematopoietic stem cell collection in healthy donors
Zhongguo shuxue zazhi[Objective] To explore the key factors affecting the efficiency and safety of hematopoietic stem cell apheresis. [Methods] The clinical data of 59 healthy donors who underwent allogeneic hematopoietic stem cell donation in the First Affiliated Hospital ...
HE Rui +5 more
doaj +1 more source
Haematologica, 2015 Expansion of erythroblasts from human peripheral blood mononuclear cells is 4- to 15-fold more efficient than that of CD34+ cells purified from peripheral blood mononuclear cells.
Esther Heideveld +7 more
doaj +1 more source