Results 121 to 130 of about 286,717 (340)

Correlation Study on HLA-DR and CD117 (c-Kit) Expressions: Its Prognosis and Treatment Response in Acute Myeloid Leukemia Patients

Pharmacogenomics and Personalized Medicine, 2021
Yomna M El-Meligui,1 Heba E Abd Elrhman,2 Ahmad Salahuddin,3 Manal Ali Hamouda,4 Amira B Kassem5 1Department of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt; 2Department of Clinical Pathology, Faculty of Medicine, Zagazig
El-Meligui YM, Abd Elrhman HE, Salahuddin A, Hamouda MA, Kassem AB   +4 more
doaj  

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

DFO Enhances the Targeting of CD34-Positive Cells and Improves Neovascularization [PDF]

, 2015
Zijing Du, Tao Zan, Xiaolu Huang, Lingling Sheng, Haizhou Li, Hua Li, Qingfeng Li   +6 more
openalex   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Correlation between P-glycoprotein and CD34 Expressions in Leukemic Cells from De novo Acute Myeloid Leukemia

Biomolecular and Health Science Journal
Introduction: Acute myeloid leukemia (AML) is a clonal cancer that develops from myeloid progenitors. P-glycoprotein (Pgp) is the membrane transporter encoded by the multidrug resistance (MDR1) gene, which is responsible for the efflux of several ...
Yulia Nadar Indrasari, Yetti Hernaningsih, Aryati Aryati, Siprianus Ugroseno Yudho Bintoro, Atika Atika, Rosline Hassan   +5 more
doaj   +1 more source

Role of angiogenesis in oral submucous fibrosis using vascular endothelial growth factor and CD34: An immunohistochemical study

Indian Journal of Dental Research, 2019
Background: Oral submucous fibrosis (OSF) is an insidious, chronic, disabling disease, in which there is lack of perfusion due to reduced level of the vasculature and this is said to be responsible for the epithelial atrophy seen in OSF.
Ettishree Sharma, Nutan Tyagi, Vineeta Gupta, Anjali Narwal, Hitesh Vij, Dheeraj Lakhnotra   +5 more
doaj   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression

, 2016
Angiogenesis involves the formation of new blood vessels by sprouting or splitting of existing blood vessels. During sprouting, a highly motile type of endothelial cell, called the tip cell, migrates from the blood vessels followed by stalk cells, an ...
Dallinga, Marchien G., Klaassen, Ingeborg, Merks, Roeland M. H., Palm, Margriet M., Schlingemann, Reinier O., van Dijk, Erik   +5 more
core   +3 more sources

Human XCR1+ Dendritic Cells Derived In Vitro from CD34+ Progenitors Closely Resemble Blood Dendritic Cells, Including Their Adjuvant Responsiveness, Contrary to Monocyte-Derived Dendritic Cells [PDF]

, 2014
Sreekumar Balan, Vincent Ollion, Nicholas Colletti, Rabie Chelbi, Frédéric Montañana-Sanchis, Hong Liu, Thien‐Phong Vu Manh, Cindy Sanchez, Juliette Savoret, Ivan Perrot, Anne‐Claire Doffin, Even Fossum, Didier Bechlian, Christian Chabannon, Bjarne Bogen, Carine Asselin‐Paturel, Michael H. Shaw, Timothy Soos, Christophe Caux, Jenny Valladeau‐Guilemond, Marc Dalod   +20 more
openalex   +1 more source