CD34+ or CD34−: which is the more primitive? [PDF]
Remarkable progress has been achieved in the characterization and isolation of primitive hematopoietic stem cells (HSC). HSC represent a very small subset of hematopoietic cells and provide self-renewal, possess differentiation capacity and allow a constant supply of the entire hematopoietic cell spectrum.
Engelhardt, Monika +2 more
openaire +3 more sources
Angiogenesis (neoangiogenesis) characterized by the formation of new blood vessels from pre-existing vessels is the main condition for the intensive growth of the primary tumor.
I. V. Stepanov +7 more
doaj +1 more source
Immunolocalization of Cd34 Positive Progenitor Cells in Diabetic and Non Diabetic Periodontitis Patients – A Comparative Study [PDF]
Background: Little research has been documented to determine the CD34 positive cells in healthy periodontium, chronic periodontitis and in chronic periodontitis with diabetes mellitus individuals. Aim: The aim of the present study was to evaluate and
Sathyanarayana Baddam +6 more
doaj +1 more source
Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report
A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that included fatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs.
T. Yaman, A. Uyar, O.F. Keles, Z. Yener
doaj +1 more source
Primary Epithelioid Angiosarcoma of Spleen: A Case Report and Review of Literature [PDF]
Splenic angiosarcomas are usually secondary tumours, and only few primary cases have been encountered. We report a unique primary case of epithelioid angiosarcoma arising in the spleen in a male patient 55-year-old and presented to our hospital as a ...
Rania Abdallah Abdallah +4 more
doaj +1 more source
Gastrointestinal Stromal Tumors of Small Intestine
Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract.
Tanweerul Huda, Mahendra Pratap Singh
doaj +1 more source
Assessment of P53 BCL-2 and CD34 in premalignant and malignant cervical lesions [PDF]
Background: Cancer cells are characterized by loss of tumor suppressor genes, evasion of apoptosis and an upregulation in angiogenesis. Cervical cancer is the second most prominent cancer amongst young women of reproductive age after breast cancer.
Ekundina Victor Olukayode +5 more
doaj
Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration. [PDF]
PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human
Annett, Geralyn +10 more
core +2 more sources
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
core +1 more source
Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison +3 more
core +2 more sources

