Stem Cell Antigen CD34 In Native And Engineered Form Alter Its Binding Ability To Stromal Cells And Ligands: A Classical Example Of Clinical Benefits Of Therapeutic Genetic Engineering Of Stem Cells In Transplantation [PDF]
CD34 is a highly glycosylated surface-expressed sialomucin and, because it is present on hematopoietic stem cells (HSCs), has demonstrated immense clinical utility in their enumeration in aphaeresis products, immunoaffinity purification for ...
Gurudutta Gangenahalli +5 more
core +2 more sources
Angiogenesis (neoangiogenesis) characterized by the formation of new blood vessels from pre-existing vessels is the main condition for the intensive growth of the primary tumor.
I. V. Stepanov +7 more
doaj +1 more source
Immunolocalization of Cd34 Positive Progenitor Cells in Diabetic and Non Diabetic Periodontitis Patients – A Comparative Study [PDF]
Background: Little research has been documented to determine the CD34 positive cells in healthy periodontium, chronic periodontitis and in chronic periodontitis with diabetes mellitus individuals. Aim: The aim of the present study was to evaluate and
Sathyanarayana Baddam +6 more
doaj +1 more source
Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report
A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that included fatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs.
T. Yaman, A. Uyar, O.F. Keles, Z. Yener
doaj +1 more source
Primary Epithelioid Angiosarcoma of Spleen: A Case Report and Review of Literature [PDF]
Splenic angiosarcomas are usually secondary tumours, and only few primary cases have been encountered. We report a unique primary case of epithelioid angiosarcoma arising in the spleen in a male patient 55-year-old and presented to our hospital as a ...
Rania Abdallah Abdallah +4 more
doaj +1 more source
Gastrointestinal Stromal Tumors of Small Intestine
Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract.
Tanweerul Huda, Mahendra Pratap Singh
doaj +1 more source
Assessment of P53 BCL-2 and CD34 in premalignant and malignant cervical lesions [PDF]
Background: Cancer cells are characterized by loss of tumor suppressor genes, evasion of apoptosis and an upregulation in angiogenesis. Cervical cancer is the second most prominent cancer amongst young women of reproductive age after breast cancer.
Ekundina Victor Olukayode +5 more
doaj
Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison +3 more
core +2 more sources
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
core +1 more source
Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]
Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL +3 more
core +1 more source

