Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells [PDF]
Several studies have reported endothelial cell (EC) derivation from human induced pluripotent stem cells (hiPSCs). However, few have explored their functional properties in depth with respect to line-to-line and batch-to-batch variability and how they ...
Freund, Christian +6 more
core +7 more sources
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo [PDF]
We treated 10 children with X-linked SCID (SCID-X1) using gammaretrovirus-mediated gene transfer. Those with sufficient follow-up were found to have recovered substantial immunity in the absence of any serious adverse events up to 5 years after treatment.
Kerstin Schwarzwaelder +53 more
core +2 more sources
Effects of Bevacizumab Injection on the Skin Wound Healing in Cynomolgus Monkeys
ObjectiveBy observing the impact of Bevacizumab injection on the speed of wound healing and the expression of CD34 in cynomolgus monkeys, to verify its delayed wound healing mechanism, and to provide clinical reference for the dosage and frequency of ...
YANG Ping, CUI Li, YU Cheng, WEN Zhiyue
doaj +1 more source
Omacetaxine may have a role in chronic myeloid leukaemia eradication through downregulation of Mcl-1 and induction of apoptosis in stem/progenitor cells [PDF]
Chronic myeloid leukaemia (CML) is maintained by a rare population of tyrosine kinase inhibitor (TKI)-insensitive malignant stem cells. Our long-term aim is to find a BcrAbl-independent drug that can be combined with a TKI to improve overall disease ...
A Quintas-Cardama +27 more
core +1 more source
Background Although recurrence of basal cell carcinoma (BCC) is uncommon, it may pose a prognostic problem that cannot be fully predicted. Aim The aim was to assess the clinical, histologic, and immunohistochemical features of recurrent BCC among ...
Maha Sultan +3 more
doaj +1 more source
Stem Cell Antigen CD34 In Native And Engineered Form Alter Its Binding Ability To Stromal Cells And Ligands: A Classical Example Of Clinical Benefits Of Therapeutic Genetic Engineering Of Stem Cells In Transplantation [PDF]
CD34 is a highly glycosylated surface-expressed sialomucin and, because it is present on hematopoietic stem cells (HSCs), has demonstrated immense clinical utility in their enumeration in aphaeresis products, immunoaffinity purification for ...
Gurudutta Gangenahalli +5 more
core +2 more sources
S. aureus menyebabkan berbagai macam penyakit infeksi sistemik, seperti endokarditis, osteomielitis, sindrom kulit melepuh, pneumonia dan penyakit Toxic Shock Syndrom (TSS). Faktor virulen S.
Dia Faroka, Sri Rahayu, Muhaimin Rifa'i
doaj +1 more source
Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry [PDF]
Angiosarcomas of oral cavity and salivary gland represent 1% of all cases reported in the literature and are therefore considered as extremely rare.
Santosh Hunasgi +3 more
doaj +1 more source
Monoclonal antibodies against human CD34 antigens do not cross-react with ovine umbilical cord blood cells [PDF]
CD34 is a cell surface glycoprotein expressed by hematopoietic progenitors and endothelial cells. It is widely used in the clinic for isolation of human hematopoietic stem cells.
Antuofermo, Elisabetta +4 more
core +3 more sources
Pseudo-Kaposi’s Sarcoma: A Rare Case and Review
Yuan Li,1,2,* Wanni Li,1,* Ming Zhang,1 Xianxu Yang,1 Changxiao Yang,1 Dan Li1 1Dermatology Department, The Fifth People’s Hospital of Hainan Province, Haikou, Hainan, People’s Republic of China; 2Department of Dermatology, The First Affiliated ...
Li Y +5 more
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