Angiogenesis (neoangiogenesis) characterized by the formation of new blood vessels from pre-existing vessels is the main condition for the intensive growth of the primary tumor.
I. V. Stepanov +7 more
doaj +1 more source
Immunolocalization of Cd34 Positive Progenitor Cells in Diabetic and Non Diabetic Periodontitis Patients – A Comparative Study [PDF]
Background: Little research has been documented to determine the CD34 positive cells in healthy periodontium, chronic periodontitis and in chronic periodontitis with diabetes mellitus individuals. Aim: The aim of the present study was to evaluate and
Sathyanarayana Baddam +6 more
doaj +1 more source
Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease [PDF]
Background: Cigarette smoke induced oxidative stress has been shown to reduce silent information regulator 1 (Sirt1) levels in lung tissue from smokers and patients with COPD patients.
Akai, Masaya +11 more
core +2 more sources
Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report
A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that included fatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs.
T. Yaman, A. Uyar, O.F. Keles, Z. Yener
doaj +1 more source
Primary Epithelioid Angiosarcoma of Spleen: A Case Report and Review of Literature [PDF]
Splenic angiosarcomas are usually secondary tumours, and only few primary cases have been encountered. We report a unique primary case of epithelioid angiosarcoma arising in the spleen in a male patient 55-year-old and presented to our hospital as a ...
Rania Abdallah Abdallah +4 more
doaj +1 more source
The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors [PDF]
Chronic myeloid leukemia (CML) is initiated and maintained by the tyrosine kinase BCR-ABL which activates a number of signal transduction pathways, including PI3K/AKT signaling and consequently inactivates FOXO transcription factors.
Bhatia +38 more
core +2 more sources
Gastrointestinal Stromal Tumors of Small Intestine
Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract.
Tanweerul Huda, Mahendra Pratap Singh
doaj +1 more source
Assessment of P53 BCL-2 and CD34 in premalignant and malignant cervical lesions [PDF]
Background: Cancer cells are characterized by loss of tumor suppressor genes, evasion of apoptosis and an upregulation in angiogenesis. Cervical cancer is the second most prominent cancer amongst young women of reproductive age after breast cancer.
Ekundina Victor Olukayode +5 more
doaj
Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1. [PDF]
Investigations of anti-HIV-1 human hematopoietic stem/progenitor cell (HSPC)-based gene therapy have been performed by HIV-1 challenge after the engraftment of gene-modified HSPCs in humanized mouse models.
An, Dong Sung +13 more
core +2 more sources
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors [PDF]
In chronic myeloid leukemia (CML), tyrosine kinase inhibitor (TKI) treatment induces autophagy that promotes survival and TKI-resistance in leukemic stem cells (LSCs).
A Hamilton +42 more
core +2 more sources

