A simple model system enabling human CD34+ cells to undertake differentiation towards T cells [PDF]
, 2013 Channelling the development of haematopoietic progenitor cells into T lymphocytes is dependent upon a series of extrinsic prompts whose temporal and spatial sequence is critical for a productive outcome.
B-Lynch Christopher +11 more
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Nilotinib concentration in cell lines and primary CD34+ chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters [PDF]
, 2009 Imatinib mesylate and nilotinib are highly effective at eradicating the majority of chronic myeloid leukemia (CML) cells; however, neither agent induces apoptosis of primitive CML CD34<sup>+</sup> cells.
Holyoake, T.L. +10 more
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Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report
Veterinární Medicína, 2018 A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that included fatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs.
T. Yaman, A. Uyar, O.F. Keles, Z. Yener
doaj +1 more source
Primary Epithelioid Angiosarcoma of Spleen: A Case Report and Review of Literature [PDF]
Journal of Clinical and Diagnostic Research, 2017 Splenic angiosarcomas are usually secondary tumours, and only few primary cases have been encountered. We report a unique primary case of epithelioid angiosarcoma arising in the spleen in a male patient 55-year-old and presented to our hospital as a ...
Rania Abdallah Abdallah +4 more
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Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones [PDF]
, 2005 Adult mesenchymal stem cells with multilineage differentiation potentially exist in the bone marrow, but have also been isolated from the peripheral blood.
Moser, C. +4 more
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Gastrointestinal Stromal Tumors of Small Intestine
The Surgery Journal, 2019 Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract.
Tanweerul Huda, Mahendra Pratap Singh
doaj +1 more source
Assessment of P53 BCL-2 and CD34 in premalignant and malignant cervical lesions [PDF]
Journal of Krishna Institute of Medical Sciences University, 2022 Background: Cancer cells are characterized by loss of tumor suppressor genes, evasion of apoptosis and an upregulation in angiogenesis. Cervical cancer is the second most prominent cancer amongst young women of reproductive age after breast cancer.
Ekundina Victor Olukayode +5 more
doaj
Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]
, 2004 Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Seliger, Christian +15 more
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Inhibition of MDR1 does not sensitize primitive chronic myeloid leukemia CD34+ cells to imatinib [PDF]
, 2009 <p><b>Objective:</b> To investigate the interaction of imatinib mesylate (IM) with the clinically relevant adenosine triphosphate-binding cassette efflux transporter MDR1 (ABCB1) in cells from patients with chronic myeloid leukemia (CML)
Holyoake, T.L. +4 more
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Hepatocyte growth factor and carotid intima-media thickness in relation to circulating CD34-positive cell levels [PDF]
, 2018 Hepatocyte growth factor (HGF) may act as a possible biochemical index for vascular damage, although evidence for the association between HGF and carotid intima-media thickness (CIMT) is limited. Since both HGF and circulating CD34-positive cells play an
Kawashiri, Shin-Ya +23 more
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