Results 51 to 60 of about 5,353 (192)

Twenty-four-color full spectrum flow cytometry panel for minimal residual disease detection in acute myeloid leukemia

Open Medicine, 2023
Full spectrum flow cytometry brings a breakthrough for minimal residual disease (MRD) detection in acute myeloid leukemia (AML). We aimed to explore the role of a new panel in MRD detection. We established a 24-color full-spectrum flow cytometry panel. A
Chen Man, Fu Minjing, Gong Meiwei, Gao Yajing, Wang Aixian, Zhao Wei, Wu Xueying, Wang Hui   +7 more
doaj   +1 more source

ACUTE LEUKEMIA OF MIXED B, T AND MYELOID PHENOTYPE WITH COMPLEX KARYOTYPE: TREATABLE DISEASE OR DEATH SENTENCE?

Hematology, Transfusion and Cell Therapy, 2023
The case was attended by our team at Santa Casa de São José dos Campos, a teaching hospital with Accreditation Level 3 from National Accreditation Organization, classified as structuring hospital by the government of the State of São Paulo, which serves ...
DTK Obikawa, LA Vianna, AAM Zung, ES Rosa, F Callera   +4 more
doaj   +1 more source

Irradiation‐Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK

Immunology, EarlyView.
Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Estelle Leplus, Jamila Kacher, Dalil Hannani, Guillaume Vayssiere, Jean‐Paul Molens, Karine Laulanier, Dan Georgess, Véronique Josserand, Philippe Saas, Séverine Planel, Laurence Chaperot, Joel Plumas   +11 more
wiley   +1 more source

Abnormal surface markers expression on bone marrow CD34+ cells and correlation with disease activity in patients with systemic lupus erythematosus

, 2007
Defects of hematopoietic stem cells (HSCs) have been suggested to contribute to the development of systemic lupus erythematosus (SLE). The aim of this study was to investigate the phenotypic characteristics of bone marrow (BM) CD34+ cells in patients ...
Lau, CS, Sun, LY, Zhou, KX, Fan, LM, Ding, XQ, Feng, XB, Zhang, HY, Jin, O, Lu, LW, Hou, YY   +9 more
core   +1 more source

CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

, 2010
Acute myeloid leukemia (AML) with mutated NPM1 shows distinctive biologic and clinical features, including absent/low CD34 expression, the significance of which remains unclear. Therefore, we analyzed CD34+ cells from 41 NPM1-mutated AML.
Christian Thiede, Linda Giunchi, Massimo F. Martelli, Franca Falzetti, Debora Cecchini, Mario Delia, Maria Paola Martelli, Mauro Di Ianni, Elisabetta Bonifacio, Roberta Pacini, Marica Gemei, Raffaella Ciurnelli, Nicla Manes, Ilaria Gionfriddo, Brunangelo Falini, Valentina Pettirossi, Federica Mezzasoma, Uta Oelschlägel, Lorenzo Brunetti, Giorgina Specchia, Francesco Di Raimondo, Luigi Del Vecchio, Arcangelo Liso, Alessia Tabarrini, Roberta Rossi   +24 more
core   +2 more sources

UNRAVELING RARE CASES IN ACUTE MYELOID LEUKEMIAS: THE SIGNIFICANCE OF SPECIALIZED REMOTE LABORATORIES IN HEMATOLOGICAL DIAGNOSIS

Hematology, Transfusion and Cell Therapy, 2023
Introduction: The diagnosis of onco-hematologic conditions in medical and hospital settings typically involves relying on centralized reference laboratories for investigative and clinical-laboratory diagnostic support.
S Lanes, LA Mattos, MAM Morais, APS Lima, C Pugliesi, M Souza, R Prot-Siqueira, A Marinato   +7 more
doaj   +1 more source

Supplementary Figure 3 from A Leukemia-Associated CD34/CD123/CD25/CD99⁺ Immunophenotype Identifies <i>FLT3</i>-Mutated Clones in Acute Myeloid Leukemia

, 2023
<p>Supplementary Figure 3. MPFC and molecular analysis of UPN 241 bone marrow samples at diagnosis, during follow-up and at relapse.</p>
Francesco Lo-Coco, Luca Battistini, Adriano Venditti, Sergio Amadori, Giorgio Bernardi, Giovanna Borsellino, Maria Irno Consalvo, Nélida I. Noguera, Mariadomenica Divona, Luca Maurillo, Francesca Gargano, Marco De Bardi, Francesco Buccisano, Michela Cittadini, Serena Lavorgna, Gisella Guerrera, Tiziana Ottone, Daniela F. Angelini   +17 more
openaire   +1 more source

Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Resistance to venetoclax has become a critical bottleneck limiting its long‐term clinical benefits. A thorough understanding of the underlying resistance mechanisms and the development of novel strategies to overcome resistance are central to improving survival outcomes in elderly AML patients. Abstract To date, the treatment of acute myeloid leukaemia
Jinlin Zhang, Jile Liu, Mohan Zhao, Xiaoyu Zhang, Linlin Liu, Mengnan Li, Changze Cao, Rui Zhang, Mingfeng Zhao   +8 more
wiley   +1 more source

Correlation Analysis and Prognostic Impacts of Biological Characteristics in Elderly Patients with Acute Myeloid Leukemia

Clinical Interventions in Aging, 2022
Fengli Li,1 Na Li,2 Anyou Wang,1,2 Xin Liu1,2 1Department of Hematology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, People’s Republic of China; 2Department of Hematology, The First Affiliated Hospital of USTC, Division of ...
Li F, Li N, Wang A, Liu X
doaj  

Supplementary Table 1 from A Leukemia-Associated CD34/CD123/CD25/CD99⁺ Immunophenotype Identifies <i>FLT3</i>-Mutated Clones in Acute Myeloid Leukemia

, 2023
<p>Supplementary Table 1. anti-human antibodies used.</p>
Francesco Lo-Coco, Luca Battistini, Adriano Venditti, Sergio Amadori, Giorgio Bernardi, Giovanna Borsellino, Maria Irno Consalvo, Nélida I. Noguera, Mariadomenica Divona, Luca Maurillo, Francesca Gargano, Marco De Bardi, Francesco Buccisano, Michela Cittadini, Serena Lavorgna, Gisella Guerrera, Tiziana Ottone, Daniela F. Angelini   +17 more
openaire   +1 more source