Results 121 to 130 of about 83,609 (361)

Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice [PDF]

, 2009
We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment.
A Chroni, A Duka, A Patsialou, A Rigotti, A Walsh, AP Feinberg, B Staels, B Staels, B Staels, B Staels, B Staels, B Staels, BN Finck, CW Miller, D Arsenijevic, D Lan, D Sanoudou, D Sanoudou, D Sanoudou, EM Rubin, ES Cathcart, F Yadetie, G Fredrikson, G Martin, H Duez, H Samyn, HB Rubins, HY Kan, J Karbowska, J Lin, J St Pierre, JC Fruchart, JD Brunzell, JJ Lehman, JK Reddy, JL Goldstein, JM Huss, JM Huss, JP Desager, K C Hayes, K Drosatos, K Motojima, K Schoonjans, K Schoonjans, KE Kypreos, KE Kypreos, KS Frederiksen, L Berthou, LA Pennacchio, LJ Kelly, M Bouly, MB Eisen, MC Hunt, MJ Holness, N Hennuyer, N Vu-Dac, N Vu-Dac, N Vu-Dac, N Vu-Dac, NF Cariello, P Puigserver, Q Guo, R Sladek, RB Vega, RL Jacobs, SA Greenberg, SN Schreiber, V Beisvag, V Giguere, V I Zannis, V Litvak, VG Tusher, VI Zannis, VI Zannis, VI Zannis, WC Roberts, X Prieur, Y Kamei, Y Nagai, Z Wu   +79 more
core   +3 more sources

Extracellular Vesicles From Limosilactobacillus johnsonii Enhance Milk Fat Synthesis by Inducing CD36 Dynamic Palmitoylation and Activating PPARγ Signalling. [PDF]

J Extracell Vesicles
Extracellular vesicles from Limosilactobacillus johnsonii reach the mammary gland through the gut‐mammary axis, where their palmitic acid (C16:0) induce the dynamic changes in CD36 palmitoylation in mammary epithelial cells, thereby facilitating fatty acid uptake as substrates and enhance milk fat synthesis in HC11 cells via PPARγ signalling.
Li Q, Li B, Zhang Q, Chen D, Yuan S, Jing H, Li H, Guan W, Zhang S.   +8 more
europepmc   +2 more sources

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

CD36 promotes the epithelial–mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β

Journal of Translational Medicine, 2019
Background Accumulating evidence indicates that CD36 initiates metastasis and correlates with an unfavorable prognosis in cancers. However, there are few reports regarding the roles of CD36 in initiation and metastasis of cervical cancer.
Min Deng, Xiaodong Cai, Ling Long, Linying Xie, Hongmei Ma, Youjian Zhou, Shuguang Liu, Chao Zeng   +7 more
doaj   +1 more source

Activation of AMPKα2 Is Not Required for Mitochondrial FAT/CD36 Accumulation during Exercise. [PDF]

PLoS ONE, 2015
Exercise has been shown to induce the translocation of fatty acid translocase (FAT/CD36), a fatty acid transport protein, to both plasma and mitochondrial membranes.
Cynthia Monaco, Jamie Whitfield, Swati S Jain, Lawrence L Spriet, Arend Bonen, Graham P Holloway   +5 more
doaj   +1 more source

Induction of CD36 and Thrombospondin-1 in Macrophages by Hypoxia-Inducible Factor 1 and Its Relevance in the Inflammatory Process [PDF]

, 2012
Inflammation is part of a complex biological response of vascular tissue to pathogens or damaged cells. First inflammatory cells attempt to remove the injurious stimuli and this is followed by a healing process mediated principally by phagocytosis of ...
Barrachina Sancho, María Dolores, Calatayud Romero, Sara, Cosín Roger, Jesús, Díez, Irene, Esplugues Mota, Juan Vicente, Hernández, Carlos, Ortiz Masiá, María Dolores   +6 more
core   +2 more sources

An association analysis between the variability of the caprine CD36 and CD36-like genes and dairy traits

Small Ruminant Research, 2014
The CD36 molecule plays a key role in the uptake of long-chain fatty acids. In a previous study, we demonstrated that the CD36 gene is duplicated in goats. Moreover, both copies (CD36 and CD36-like) display highly divergent mRNA expression profiles. Herewith, we have analyzed whether four polymorphisms mapping to CD36 (c.394A > G, c.*141C > T and c ...
Zidi, Ali, Jordana, Jordi, Fernández-Cabanás, Víctor M., Urrutia, Baltasar, Carrizosa, Juan, Polvillo, Oliva, González-Redondo, Pedro, Gallardo, David, Serradilla, Juan Manuel, Amills, Marcel   +9 more
openaire   +3 more sources

Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells

Frontiers in Oncology, 2020
Fatty acid synthase, a key enzyme of de novo lipogenesis, is an attractive therapeutic target in cancer. The novel fatty acid synthase inhibitor, TVB-3664, shows anti-cancer activity in multiple cancers including colorectal cancer; however, it is unclear
J. Drury, P. Rychahou, Daheng He, N. Jafari, Chi Wang, Eun Y. Lee, H. Weiss, B. Evers, Yekaterina Y. Zaytseva   +8 more
semanticscholar   +1 more source

The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion

Advanced Science, EarlyView.
Clinical discovery and the proposed underlying mechanism by how P. johnsonii ameliorated metabolic disorders. Abstract The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. However, the role of Parabacteroides johnsonii in metabolic disorders is never reported.
Yimeng Chen, Shujun Jiang, Haolu Wang, Mengzhen Si, Haixia Wu, Xinyi Liang, Shenmeng Yao, Yanliang Zhang, Xiaodong Wen, Jie Yang   +9 more
wiley   +1 more source

CD36 tango in cancer: signaling pathways and functions

Theranostics, 2019
CD36, a scavenger receptor expressed in multiple cell types, mediates lipid uptake, immunological recognition, inflammation, molecular adhesion, and apoptosis.
Jing-chun Wang, Yongsheng Li
semanticscholar   +1 more source