Results 151 to 160 of about 42,741 (260)

Cytogenetic and Molecular Analysis of a “Double‐Hit” RUNX1 Including a RUNX1 p.Trp279* and a Cryptic Novel t(6;21)(q25;q22)/RUNX1::ARID1B in Acute Myeloid Leukemia

Genes, Chromosomes and Cancer, Volume 65, Issue 6, June 2026.
ABSTRACT Introduction Alterations involving RUNX1 are recurrent in hematologic malignancies and contribute to disease pathogenesis via dysregulation of transcriptional factors essential for hematopoiesis. Here, we report an acquired alteration in both alleles of RUNX1; one is a truncating mutation and the second is a novel RUNX1::ARID1B identified in ...
Rolando García, Jing Xu, Lan Yu, Kalayarasan Srinivasan, Sharon Koorse Germans, Olga Weinberg, Franklin Fuda, Weina Chen, Prasad Koduru   +8 more
wiley   +1 more source

Loss of peroxisomal membrane proteins PEX13 and PEX14 disrupts fatty acid oxidation and drives lipid imbalance. [PDF]

Biosci Rep
Vinoy N, Huang G, Wallace D, Subramaniam VN.   +3 more
europepmc   +1 more source

Characterization of Genes Related to Intramuscular Fat Deposition in Muscles of Piglets Under Cold Exposure by Whole Transcriptome Sequencing. [PDF]

Curr Issues Mol Biol
Wang F, Wang L, Guo Z, Ma H, Fu B, Zhang D, Liu D.   +6 more
europepmc   +1 more source

Simulated microgravity models sex differences in knee osteoarthritis through a CD36-regulated mechano-metabolic circuit. [PDF]

Cell Commun Signal
Ma Z, Lin H, Young D, Ansari A, Kunze M, Mulet-Sierra A, Febbraio M, Graf D, Dufour A, Adesida AB.   +9 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Phagocytosis is crucial for brain repair. [PDF]

J Cereb Blood Flow Metab
Lyu J, Zhang W, Wu WC, Leak R, Chen J.
europepmc   +1 more source

DAMP Laden Extracellular Vesicles From the Airways of Patients With Severe SARS‐CoV‐2 Respiratory Infection Compromise Inflammation and Cellular Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Extracellular vesicles from severe COVID‐19 airways carry depleted miRNAs and elevated DAMPs, reprogramming monocytes toward senescence, impaired metabolism, and predominantly reduced cytokine responses. However, they drive excess IL‐8 production, amplifying neutrophil recruitment and dysfunctional inflammation across the respiratory tract.
April Rees, Oliver Richards, Molly E Raikes, Megan Chambers, Sophie G Reed, Ceri Battle, Hannah Toghill, Luke Newey, Tyler J Joseph, Haiyan An, Hui Zhang, Iain Perry, Jason Webber, Nicholas Jones, Catherine A Thornton   +14 more
wiley   +1 more source

Deuterosomal cells are the responsible lineage for multiciliogenesis in human airway differentiation. [PDF]

Stem Cell Reports
Yamaki H, Konishi S, Tamai K, Sone N, Takahashi S, Xu Y, Tsuji T, Ozasa H, Yamamoto T, Hirai T, Takeuchi K, Gotoh S.   +11 more
europepmc   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4521-4549, June 2026.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Full-length haplotype reconstruction of CD36 by long-read sequencing: uncovers a novel structural variant. [PDF]

BMC Genomics
Liang S, Liu T, Che H, Xia W, Fu W, Wu F, Sun L, Fu Y, Zhu F, Cui D.   +9 more
europepmc   +1 more source