Results 201 to 210 of about 83,609 (361)

Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-γ [PDF]

, 2000
Jianwei Feng, Jihong Han, S. Freida A. Pearce, Roy L. Silverstein, Antonio M. Gotto, David P. Hajjar, Andrew Nicholson   +6 more
openalex   +1 more source

Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer\u27s disease [PDF]

, 2020
A promising new therapeutic target for the treatment of Alzheimer\u27s disease (AD) is the circadian system. Although patients with AD are known to have abnormal circadian rhythms and suffer sleep disturbances, the role of the molecular clock in ...
Griffin, Percy, Kim, Do Eon, Kim, Dong-Hou, Lee, Jiyeon, Musiek, Erik S, Sheehan, Patrick W, Yoon, Seung-Yong   +6 more
core   +1 more source

Repetitive Transcranial Magnetic Stimulation Induces Cognitive Recovery in Alzheimer's Disease via GABAergic Neuron Activation of the Cx3cl1‐Cx3cr1 Axis

Cell Proliferation, EarlyView.
Schematic diagram illustrating the molecular mechanisms of the Cx3cl1‐Cx3cr1 axis mediated by rTMS activation of GABAergic neurons in the process of cognitive function recovery in AD. ABSTRACT This study aimed to investigate the impact of repetitive transcranial magnetic stimulation (rTMS) on cognitive recovery in Alzheimer's disease (AD) by exploring ...
Yunxiao Kang, Jilun Liu, Yu Wang, Jiaying Wang, Jinyang Wang, Chenming Zhou, Rui Cui, Tianyun Zhang   +7 more
wiley   +1 more source

Discovery and in vitro characterization of a human anti-CD36 scFv

Frontiers in Immunology
IntroductionCD36 is a membrane receptor that participates in the cellular uptake of fatty acids and lipid metabolism. CD36 overexpression favors progression of different pathologies, such as atherosclerosis and cancer.
Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez   +10 more
doaj   +1 more source

Mechanism of EC‐EXOs‐Derived THBS3 Targeting CD47 to Regulate BMSCs Differentiation to Ameliorate Bone Loss

Cell Proliferation, EarlyView.
EC‐EXOs could regulate the differentiation of BMSCs through the key protein THBS3, which inhibits their differentiation to lipogenic cells and promotes their differentiation to osteoblasts. THBS3 could down‐regulate the expression of its downstream target CD47 and delay the process of bone loss in aged mice and OVX mice, which may provide a novel ...
Jiaojiao Wang, Zhaokai Zhou, Wenjie Chen, Yun Chen, Qiyue Zheng, Yajun Chen, Zhengxiao Ouyang, Ran Xu, Qiong Lu   +8 more
wiley   +1 more source

The Integrins α3β1 and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells [PDF]

, 2000
Rick F. Thorne, John F. Marshall, Darren R. Shafren, Peter G. Gibson, Ian R. Hart, Gordon F. Burns   +5 more
openalex   +1 more source

CD36 deletion reduces VLDL secretion, modulates liver prostaglandins, and exacerbates hepatic steatosis in ob/ob mice[S]

Journal of Lipid Research, 2013
Recent findings described the role of CD36-mediated signaling in regulating cellular calcium and the release of various bioactive molecules, including the prostaglandins, neurotransmitters, cholecystokinin, and secretin. Here we document the role of CD36
Fatiha Nassir, Okunade L. Adewole, Elizabeth M. Brunt, Nada A. Abumrad   +3 more
doaj  

Cd36 knockout mice are protected against lithogenic diet-induced gallstones [PDF]

, 2017
Abumrad, Nada A., Atabai, Kamran, Cifarelli, Vincenza, Clugston, Robin, Davidson, Nicholas O., Kennedy, Susan M., Khalifeh-Soltani, Amin, Newberry, Elizabeth P., Pietka, Terri, Xie, Yan   +9 more
core   +2 more sources

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

Cell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen, Haijun Zhang, Zhaoheng Wang, Daxue Zhu, Yanhu Li, Yizhi Zhang, Dongxin Wang, Shuwei Chen, Huan Liu, Xuewen Kang   +9 more
wiley   +1 more source

Isolation and characterization of platelet glycoprotein IV (CD36)

, 1989
Narendra N. Tandon, Robert H. Lipsky, Wilson H. Burgess, Graham Jamieson   +3 more
openalex   +1 more source