Results 221 to 230 of about 42,741 (260)

CD36:A Multiligand Molecule

Laboratory Hematology, 2005
CD36 is a multiligand receptor associated with a broad array of physiological processes and involved in markedly diverse disorders, including atherosclerosis, insulin resistance and diabetes, dyslipidemia, tumor angiogenesis, and host defense against Plasmodium falciparum.
Yimin, Ge, M Tarek, Elghetany
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CD36 and taste of fat

Current Opinion in Clinical Nutrition and Metabolic Care, 2012
This review explores the recent literature on the role of CD36 in the taste of fat, eating behavior and obesity risk in rodents and humans.During the last decade, evidence was accumulated supporting the existence of a taste of fat responsible for the spontaneous preference for lipid-rich foods.
Patricia, Degrace-Passilly, Philippe, Besnard   +1 more
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CD36 is a sensor of diacylglycerides

Nature, 2005
Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components of bacteria, fungi and protozoa. The breadth of the ligand repertoire seems unusual, even if one considers that TLR2 may form heteromers with TLRs 1 and 6 (ref. 12), and it is likely that additional proteins serve as adapters for TLR2 activation.
Kasper, Hoebe, Philippe, Georgel, Sophie, Rutschmann, Xin, Du, Suzanne, Mudd, Karine, Crozat, Sosathya, Sovath, Louis, Shamel, Thomas, Hartung, Ulrich, Zähringer, Bruce, Beutler   +10 more
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Effects of aldehydes on CD36 expression

Free Radical Research, 2005
During the oil frying process lipid peroxidation compounds are formed. These products can modulate gene expression and alter cellular behaviour. The cellular uptake of oxidized LDL, a key step in the development of atherosclerosis, is mediated by the CD36 scavenger receptor, whose expression is down-regulated by alpha-tocopherol.To determine the ...
M, Viana, L, Villacorta, B, Bonet, A, Indart, A, Munteanu, I, Sánchez-Vera, A, Azzi, J M, Zingg   +7 more
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Harnessing CD36 to Rein in Inflammation

Endocrine‚ Metabolic & Immune Disorders-Drug Targets, 2008
Maintaining health requires a dynamic balance between the influence of pro-inflammatory and anti-inflammatory mediators. While inflammation serves an important protective role against infection, unrestrained inflammation is acutely lethal and unresolved inflammation contributes to a broad range of chronic disorders.
M S, Parsons, L, Barrett, C, Little, M D, Grant   +3 more
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Frequency of CD36 deficiency in Thais analyzed by quantification of CD36 on cell surfaces and in plasma

Transfusion, 2020
BACKGROUNDAnti‐CD36s, developing after transfusion or during pregnancy, play an important role in immune‐mediated bleeding disorders among Asian populations. Currently, little is known about the clinical relevance of anti‐CD36. Here, we aimed to determine the frequency of CD36 deficiency in Thais by analyzing CD36 expression on cell surfaces and in ...
Roongaroon Phuangtham, Sentot Santoso, Chanvit Leelayuwat, Patcharee Komvilaisak, Haoqiang Ding, Amornrat V. Romphruk   +5 more
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CD36 expression in the brains of SAMP8

Archives of Gerontology and Geriatrics, 2013
SAMP8, senescence accelerated mice with age-related deficits in memory and learning, are known to show age-related increases of amyloid precursor protein (APP) and immunopositivity for amyloid-β (Aβ) proteins, and moreover to be under elevated oxidative stress.
Bin, Wu, Masaki, Ueno, Takashi, Kusaka, Takanori, Miki, Yukiko, Nagai, Toshitaka, Nakagawa, Kenji, Kanenishi, Naohisa, Hosomi, Haruhiko, Sakamoto   +8 more
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Erythroid involvement in CD36 deficiency

Experimental Hematology, 2001
The CD36 molecule is expressed in platelets, monocytes, erythroblasts, and other different tissues. The two types of platelet CD36 deficiency, types I and II, are associated with the absence and presence of CD36 on monocytes, respectively. To clarify the involvement of the erythroid lineage in CD36 deficiency, we investigated the phenotype and RNA ...
K, Toba, H, Hanawa, K, Watanabe, I, Fuse, M, Masuko, S, Miyajima, M, Takahashi, M, Sakaue, T, Abo, Y, Aizawa   +9 more
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The Plasmodium falciparum–CD36 Interaction Is Modified by a Single Amino Acid Substitution in CD36

Blood, 1998
AbstractCD36 is an 88-kD glycoprotein involved in the cytoadherence ofPlasmodium falciparum–parasitized erythrocytes (PE) to endothelial cells. The molecular mechanisms involved in CD36-dependent cytoadherence were examined by expressing three CD36 homologues (human, murine, and rat) in COS-7 cells and observing their PE-binding characteristics over a ...
L, Serghides, I, Crandall, E, Hull, K C, Kain   +3 more
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The Function of CD36 in Tumorigenesis

2022
During matrix detachment, tumor cells grow as multicellular clusters, and metabolism in this setting has been shown to recapitulate early stages of tumorigenesis. We previously found that detached cells activate AMPK to inhibit fatty acid synthesis and induce fatty acid oxidation, which raises the question of how clustered cells maintain the integrity ...
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