Results 201 to 210 of about 74,406 (290)

Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1215-1235, May 2026.
Peroxisome proliferator‐activated receptor (PPAR) agonists have emerged as important second‐line treatments in primary biliary cholangitis, with profiles influenced by different selectivity for α‐, δ‐ and γ‐isoforms. PPAR‐α and PPAR‐δ agonism improve cholestasis, with inflammation reduced via all isoforms. PPAR‐δ agonism also reduces pruritus.
Jörn M. Schattenberg, Jesus M. Banales, Gideon Hirschfield, Palak Trivedi, Edward E. Cable, Charles A. McWherter, Andrew N. Billin, Daria B. Crittenden, Grant Budas   +8 more
wiley   +1 more source

Efferocytosis: Gateway for tissue resolution. [PDF]

J Cereb Blood Flow Metab
Cho S, Ju H.
europepmc   +1 more source

Growth differentiation factor 15 mitigates lipotoxic steatosis by preserving mitochondrial morphodynamics and augmenting fatty acid oxidation in hepatocytes and liver organoids

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3788-3806, May 2026.
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li, Qi Zhou, Mengmeng Xia, Yakun Li, Junyu Wang, Manon Buist‐Homan, Vincent E. de Meijer, Hans Blokzijl, Klaas Nico Faber, Han Moshage   +9 more
wiley   +1 more source

CD36-PPARγ-SPP1 axis mediates hepatocyte-macrophage coordination to drive MASLD-related liver fibrosis. [PDF]

JHEP Rep
Dai Z, Liu X, Liang Y, Zhou G, Chen F, Xie W, Lei SY, Lian LY, Chen SD, Muthiah MD, Ouyang X, Zheng MH, Wang Y.   +12 more
europepmc   +1 more source

B Cell Subsets and Atherosclerosis: Updates and Emerging Concepts

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) is increasingly recognized not just as a lipid‐driven disease, but as a complex interplay between vascular cells and the immune system. Accumulating evidence highlights a central, yet heterogeneous role for B cells in atherogenesis, with distinct subsets displaying opposing roles.
Sophieke Lems, Megan Grace Mazzei, Amanda C. Foks, Coleen A. McNamara   +3 more
wiley   +1 more source

CD36 rs1761667 Polymorphism and Its Impact on Molecular Signatures in Bladder Cancer. [PDF]

Diseases
Pavalean MI, Lambrescu IM, Gaina G, Madan VL, Hinescu ME, Ceafalan LC.   +5 more
europepmc   +1 more source

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter, João Dias‐Ferreira, Gustavo Campos Ramos, DiyaaElDin Ashour   +3 more
wiley   +1 more source

Apolipoprotein D, a Novel Ligand for CD36, Is Essential for Blood-Brain Barrier Integrity. [PDF]

Circulation
Gong CX, Shi PX, Huang YJ, Dai Y, Hu LL, Cheng XF, Zhang S, He MT, Wang JH, Meng ZY, Fang YL, Wang BQ, Zhao Y, He CK, Yang GQ, Zi WJ, Qiu ZM, Li FL, Lin S, Lu H, Zhao CH, Zhang C, Liu ZY, Dong MQ, Ouyang Q, Zheng HT, Niu JQ, Mei F, Sun BL, Zhou J, Xie Q, Li FF, Yang QW.   +32 more
europepmc   +1 more source

CD36 as an Oxidized LDL Receptor-Insight from CD36 Deficient Subjects

The Journal of Japan Atherosclerosis Society, 1996
Shuichi NOZAKI, Hirokazu KASHIWAGI, Yuji MATSUZAWA   +2 more
openaire   +2 more sources

From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak, Pola Ochocka, Karol Sadowski, Weronika Ploch, Dominika Tomkiel, Mariusz Tomaniak, Wioletta Olejarz   +6 more
wiley   +1 more source