Results 51 to 60 of about 83,373 (351)

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

open access: yesNature Immunology, 2019
Depleting regulatory T cells (T reg cells) to counteract immunosuppressive features of the tumor microenvironment (TME) is an attractive strategy for cancer treatment; however, autoimmunity due to systemic impairment of their suppressive function limits ...
Haiping Wang   +19 more
semanticscholar   +1 more source

Oxidized LDL induces alternative macrophage phenotype through activation of CD36 and PAFR [PDF]

open access: yes, 2013
OxLDL is recognized by macrophage scavenger receptors, including CD36; we have recently found that Platelet-Activating Factor Receptor (PAFR) is also involved.
Ferracini, M.   +5 more
core   +3 more sources

The intestinal lymphatic system: Functions and metabolic implications [PDF]

open access: yes, 2019
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
core   +2 more sources

CD36 Goes Native [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2008
There’s a saying that goes: “everything old is new again,” and I am reminded of this by the article by Luangrath et al1 in this issue of Arteriosclerosis, Thrombosis and Vascular Biology . Not that this article shows old data, but that what was old, now cast in a different light, leads to new ideas and hypotheses.
openaire   +3 more sources

Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking

open access: yesJCI Insight, 2021
The mechanism controlling long-chain fatty acid (LCFA) mobilization from adipose tissue is not well understood. Here, we investigated how the LCFA transporter CD36 regulates this process.
Alexes C. Daquinag   +8 more
semanticscholar   +1 more source

MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice

open access: yesCells, 2019
MicroRNA-29 (miR-29) has been shown to play a critical role in reducing inflammation and fibrosis following liver injury. Non-alcoholic fatty liver disease (NAFLD) occurs when fat is deposited (steatosis) in the liver due to causes other than excessive ...
Hung-Yu Lin   +3 more
doaj   +1 more source

Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells

open access: yesOncoImmunology, 2020
The ‘cancer cell fusion’ theory is controversial due to the lack of methods available to identify hybrid cells and to follow the phenomenon in patients.
Luis Augusto Aguirre   +39 more
doaj   +1 more source

Biological Mechanisms and Related Natural Inhibitors of CD36 in Nonalcoholic Fatty Liver

open access: yesDrug Design, Development and Therapy, 2022
Yanan Feng,1,* Wenxiu Sun,2,* Fengcui Sun,1 Guoliang Yin,1 Pengpeng Liang,1 Suwen Chen,1 Xiangyi Liu,1 Tongfei Jiang,3 Fengxia Zhang4 1Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2Department of ...
Feng Y   +8 more
doaj  

Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]

open access: yes, 2012
BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Carl Cotman   +8 more
core   +2 more sources

Molecular basis of CD36 deficiency. Evidence that a 478C-->T substitution (proline90-->serine) in CD36 cDNA accounts for CD36 deficiency. [PDF]

open access: yesJournal of Clinical Investigation, 1995
CD36 deficiency is divided into two subgroups: neither platelets nor monocytes express CD36 (type I deficiency), and monocytes express CD36 in spite of the lack of platelet CD36 (type II deficiency). We have already demonstrated that a 478C-->T substitution (proline90-->serine) in platelet CD36 cDNA predominates in type II deficiency (Kashiwagi, H., S.
Yoshio Kanayama   +9 more
openaire   +2 more sources

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