Results 71 to 80 of about 53,340 (302)

Biological Mechanisms and Related Natural Inhibitors of CD36 in Nonalcoholic Fatty Liver

Drug Design, Development and Therapy, 2022
Yanan Feng,1,* Wenxiu Sun,2,* Fengcui Sun,1 Guoliang Yin,1 Pengpeng Liang,1 Suwen Chen,1 Xiangyi Liu,1 Tongfei Jiang,3 Fengxia Zhang4 1Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2Department of ...
Feng Y, Sun W, Sun F, Yin G, Liang P, Chen S, Liu X, Jiang T, Zhang F   +8 more
doaj  

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Retinal Degeneration in CD36-Deficient Animals

, 2013
(A) CD36 Western blot analysis of RPE/choroids complexes from Wistar rats (W) and SHRs S) (n = 4 eyes per group). (B and C) CD36 expression (green fluorescence) (B) and double-labeling with vascular marker BSA-1 (CD36 [green], BSA-1 [red ...
Jean-Claude Jeanny (64433), Laurent Jonet (64432), Florian Sennlaub (64439), Marianne Houssier (64426), Daniel Scherman (52614), William Raoul (64427), Sophie Lavalette (64428), Flavio Coceani (64435), Sylvain Chemtob (64438), Pierre Lachapelle (64436), Barbara Baragatti (64431), Nicole Keller (64429), Huy Ong (64437), Xavier Guillonneau (64430), Francine Behar-Cohen (64434)   +14 more
core   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Choroidal Degeneration in CD36-Deficient Animals

, 2013
(A and B) Micrographs of the retinal aspect of choriocapillaries in a frontal view of corrosion casts by scanning electron microscopy. Choroidal vessels (darker grey) can be seen through the intercapillary spaces of the choriocapillaries in 4-mo-old SHRs
Jean-Claude Jeanny (64433), Laurent Jonet (64432), Florian Sennlaub (64439), Marianne Houssier (64426), Daniel Scherman (52614), William Raoul (64427), Sophie Lavalette (64428), Flavio Coceani (64435), Sylvain Chemtob (64438), Pierre Lachapelle (64436), Barbara Baragatti (64431), Nicole Keller (64429), Huy Ong (64437), Xavier Guillonneau (64430), Francine Behar-Cohen (64434)   +14 more
core   +1 more source

Molecular Mechanism and Therapeutic Exploration of CD36 in Breast Cancer

Zhongliu Fangzhi Yanjiu
Breast cancer is the most diagnosed cancer in women worldwide and the leading cause of most cancer-related deaths, posing a serious threat to women′s health worldwide.
FU Shengqiao, JI Qian, SUN Xinyu, PU Xi, WU Yuting, TANG Haowei, SHENG Wanying, WANG Xu   +7 more
doaj   +1 more source

Expression of genes encoding IGFBPs, SNARK, CD36, and PECAM1 in the liver of mice treated with chromium disilicide and titanium nitride nanoparticles

Endocrine Regulations, 2017
Objective. The aim of the present study was to examine the effect of chromium disilicide and titanium nitride nanoparticles on the expression level of genes encoding important regulatory factors (IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, SNARK/NUAK2, CD36,
Minchenko Dmytro O., Tsymbal D. O., Yavorovsky O. P., Solokha N. V., Minchenko O. H.   +4 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Mouse DCs express CD36 on the surface and internalize IRBCs in a CD36-dependent manner.

, 2013
A. The expression of CD36 on the surface of mDC and pDC populations of mouse FL-DCs as assessed by flow cytometry after staining with anti-mouse CD36 monoclonal antibody.
D. Channe Gowda (91625), Xianzhu Wu (218234), Sanjeev Kumar (101140), Nagaraj M. Gowda (218231), Maria Febbraio (65515)   +4 more
core   +1 more source

Whole-genome polymorphism of CD36 by third-generation sequencing technology

Zhongguo shuxue zazhi
[Objective] To analyze CD36 gene by PacBio Sequel Ⅱ the third-generation sequencing technology (TGS), including non-coding sequence, and to investigate the molecular mechanism of CD36 deficiency.
LIU Jing, XU Xiuzhang, DING Haoqiang, DENG Jing, CHEN Yangkai, XIA Wenjie, YE Xin   +6 more
doaj   +1 more source