Results 51 to 60 of about 42,741 (260)

Biological Mechanisms and Related Natural Inhibitors of CD36 in Nonalcoholic Fatty Liver

Drug Design, Development and Therapy, 2022
Yanan Feng,1,* Wenxiu Sun,2,* Fengcui Sun,1 Guoliang Yin,1 Pengpeng Liang,1 Suwen Chen,1 Xiangyi Liu,1 Tongfei Jiang,3 Fengxia Zhang4 1Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2Department of ...
Feng Y, Sun W, Sun F, Yin G, Liang P, Chen S, Liu X, Jiang T, Zhang F   +8 more
doaj  

Malaria susceptibility and CD36 mutation

Nature, 2000
A critical step in infection by Plasmodium falciparum, the microorganism that causes the most severe form of malaria, is the adhesion of parasitized red blood cells to capillary endothelium. The human protein CD36 is a major receptor for P. falciparum-infected red blood cells1,2 and may contribute to the disease by sequestering infected red blood ...
Aitman, T, Cooper, L, Norsworthy, P, Wahid, F, Gray, J, Curtis, B, McKeigue, P, Kwiatkowski, D, Greenwood, B, Snow, R, Hill, A, Scott, J   +11 more
openaire   +3 more sources

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice

Journal of Lipid Research, 2003
CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and triglyceride (TG) levels and decreased glucose levels.
Jeltje R. Goudriaan, Vivian E.H. Dahlmans, Bas Teusink, D. Margriet Ouwens, Maria Febbraio, J. Anton Maassen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol   +8 more
doaj   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Molecular Mechanism and Therapeutic Exploration of CD36 in Breast Cancer

Zhongliu Fangzhi Yanjiu
Breast cancer is the most diagnosed cancer in women worldwide and the leading cause of most cancer-related deaths, posing a serious threat to women′s health worldwide.
FU Shengqiao, JI Qian, SUN Xinyu, PU Xi, WU Yuting, TANG Haowei, SHENG Wanying, WANG Xu   +7 more
doaj   +1 more source

Expression of genes encoding IGFBPs, SNARK, CD36, and PECAM1 in the liver of mice treated with chromium disilicide and titanium nitride nanoparticles

Endocrine Regulations, 2017
Objective. The aim of the present study was to examine the effect of chromium disilicide and titanium nitride nanoparticles on the expression level of genes encoding important regulatory factors (IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, SNARK/NUAK2, CD36,
Minchenko Dmytro O., Tsymbal D. O., Yavorovsky O. P., Solokha N. V., Minchenko O. H.   +4 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Whole-genome polymorphism of CD36 by third-generation sequencing technology

Zhongguo shuxue zazhi
[Objective] To analyze CD36 gene by PacBio Sequel Ⅱ the third-generation sequencing technology (TGS), including non-coding sequence, and to investigate the molecular mechanism of CD36 deficiency.
LIU Jing, XU Xiuzhang, DING Haoqiang, DENG Jing, CHEN Yangkai, XIA Wenjie, YE Xin   +6 more
doaj   +1 more source

Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice.

PLoS ONE, 2010
CD36 facilitates oxidized low density lipoprotein uptake and is implicated in development of atherosclerotic lesions. CD36 also binds unmodified high and very low density lipoproteins (HDL, VLDL) but its role in the metabolism of these particles is ...
Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, Nada A Abumrad   +6 more
doaj   +1 more source