Results 81 to 90 of about 74,406 (290)

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Molecular Mechanism and Therapeutic Exploration of CD36 in Breast Cancer

Zhongliu Fangzhi Yanjiu
Breast cancer is the most diagnosed cancer in women worldwide and the leading cause of most cancer-related deaths, posing a serious threat to women′s health worldwide.
FU Shengqiao, JI Qian, SUN Xinyu, PU Xi, WU Yuting, TANG Haowei, SHENG Wanying, WANG Xu   +7 more
doaj   +1 more source

Expression of genes encoding IGFBPs, SNARK, CD36, and PECAM1 in the liver of mice treated with chromium disilicide and titanium nitride nanoparticles

Endocrine Regulations, 2017
Objective. The aim of the present study was to examine the effect of chromium disilicide and titanium nitride nanoparticles on the expression level of genes encoding important regulatory factors (IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, SNARK/NUAK2, CD36,
Minchenko Dmytro O., Tsymbal D. O., Yavorovsky O. P., Solokha N. V., Minchenko O. H.   +4 more
doaj   +1 more source

Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice.

PLoS ONE, 2010
CD36 facilitates oxidized low density lipoprotein uptake and is implicated in development of atherosclerotic lesions. CD36 also binds unmodified high and very low density lipoproteins (HDL, VLDL) but its role in the metabolism of these particles is ...
Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, Nada A Abumrad   +6 more
doaj   +1 more source

Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer\u27s disease [PDF]

, 2020
A promising new therapeutic target for the treatment of Alzheimer\u27s disease (AD) is the circadian system. Although patients with AD are known to have abnormal circadian rhythms and suffer sleep disturbances, the role of the molecular clock in ...
Griffin, Percy, Kim, Do Eon, Kim, Dong-Hou, Lee, Jiyeon, Musiek, Erik S, Sheehan, Patrick W, Yoon, Seung-Yong   +6 more
core   +1 more source

Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]

, 2012
BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Carl Cotman, Erik Hrabovszky, Imre Kalló, István Likó, Miklós Sárvári, Nicole Berchtold, Norbert Solymosi, Sárvári, Miklós, Zsolt Liposits   +8 more
core   +2 more sources

Variants of CD36 gene and their association with CD36 protein expression in platelets.

Blood transfusion = Trasfusione del sangue, 2014
The relationship between CD36 expression level in platelets and polymorphism of the CD36 gene still needs to be explored. Here, we investigated polymorphisms of the CD36 gene and CD36 expression level in platelets in the Chinese Han population.A total of 477 samples were sequenced for exons 2 to 14 of the CD36 gene using a polymerase chain reaction ...
Xianguo, Xu, Ying, Liu, Xiaozhen, Hong, Shu, Chen, Kairong, Ma, Xiaofei, Lan, Yanling, Ying, Ji, He, Faming, Zhu, Hangjun, Lv   +9 more
openaire   +2 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Whole-genome polymorphism of CD36 by third-generation sequencing technology

Zhongguo shuxue zazhi
[Objective] To analyze CD36 gene by PacBio Sequel Ⅱ the third-generation sequencing technology (TGS), including non-coding sequence, and to investigate the molecular mechanism of CD36 deficiency.
LIU Jing, XU Xiuzhang, DING Haoqiang, DENG Jing, CHEN Yangkai, XIA Wenjie, YE Xin   +6 more
doaj   +1 more source

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]

, 2016
Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia, Aoki, Maria del Pilar, Cabalén, María Eugenia, Cabral, Maria Fernanda, Cano, Roxana Carolina, Gea, Susana, Onofrio, Luisina Inés, Ponce, Nicolás Eric, Sanmarco, Liliana Maria   +8 more
core   +4 more sources