Results 151 to 160 of about 67,119 (304)

Successful allo‐hematopoietic stem cell transplantation using washed hematopoietic stem cells in a pediatric patient complicated by acute myeloid leukemia and severe anaphylaxis to blood product

Pediatric Investigation, EarlyView.
Jieyu Tian, Guanghua Zhu, Maoquan Qin, Chenguang Jia, Shuxuan Ma, Bin Wang, Yanhui Luo   +6 more
wiley   +1 more source

Diverging in Vivo Immune Response Patterns After Oral Food Challenge in Peanut Allergic Adults

Clinical &Experimental Allergy, EarlyView.
After the oral food challenge, peanut (PN)‐allergic adults were monitored over 4 weeks, which revealed diverging immune response patterns, with strong responders (SR) exhibiting heightened Ara h 2+ B cell expansion, PN sIgE induction and increasing PN‐specific Tconv. Weak responders (WR) had more activated PN‐specific Tregs.
Florent Fauchère, Aikaterina Alexiou, Veronika Höfer, Kirsten Beyer, Sabine Dölle‐Bierke, Andreas Thiel, Margitta Worm, Julian Braun   +7 more
wiley   +1 more source

CD38 promotes hematopoietic stem cell dormancy

Hematopoietic stem cells (HSCs) are rare cells that continuously regenerate the entire hematopoietic system by producing billions of blood cells. Dormant HSCs (dHSCs) represent a distinct subpopulation of HSCs characterized by deep quiescence and very ...
Ibneeva, Liliia
core   +1 more source

A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells

Cell Proliferation, EarlyView.
This study presents a 3D bioprinted platform using gelatin‐hyaluronic acid hydrogels to enhance primary AML cell survival and proliferation while preserving stem‐like properties in vitro. By recapitulating in vivo‐like metabolic activity and drug resistance, this system offers a robust tool for preclinical drug screening and personalised therapy ...
Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma   +10 more
wiley   +1 more source

Targeting capacity, safety and efficacy of engineered extracellular vesicles delivered by transdermal microneedles to treat plasmacytoma in mice

Clinical and Translational Medicine
Background Engineered extracellular vesicles (EVs) are emerging as a highly potential platform for targeted drug delivery in cancer therapy. Although intravenous injection is commonly used in EV treatment, there is growing interest in using microneedles (
Yulin Cao, Xuan Hu, Di Wu, Yuxuan Jiang, Yali Yu, Shan Wang, Wenlan Chen, Yaoying Long, Liuyue Xu, Jiao Qu, Bianlei Yang, Blal Chakhabi, Hongxiang Wang, Yong Deng, Lei Chen, Zhichao Chen, Qiubai Li   +16 more
doaj   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

CD38 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Linked collectors and determiners for: Estudios bióticos: Plantas, artropofauna edáfica, anfibios y aves del Complejo de Páramos Iguaque Merchán.

Natural history specimen data linked to collectors and determiners held within, "Estudios bióticos: Plantas, artropofauna edáfica, anfibios y aves del Complejo de Páramos Iguaque Merchán".
Bionomia
core   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Retreatment with talquetamab and pomalidomide in triple‐class–BCMA–GPRC5D refractory myeloma

British Journal of Haematology, EarlyView.
Kian J. Rahbari, Gliceida M. Galarza Fortuna, Bhagirathbhai Dholaria, Douglas W. Sborov, Muhamed Baljevic   +4 more
wiley   +1 more source