Novel Roles for the Ectoenzyme CD38 in the Maintenance of Transcriptional and Metabolic Homeostasis in Astrocytes. [PDF]
Basak S +15 more
europepmc +1 more source
What's new? Cavity carcinomatosis, a late manifestation of cancer, fuels tumor formation throughout a large area, most commonly the peritoneal and pleural cavities. The condition also can lead to resistance to otherwise effective treatment strategies.
Zhongqiao Lin +6 more
wiley +1 more source
CD38 degrades MAVS through mitophagy to inhibit type I interferon secretion in nasopharyngeal carcinoma cells and impairs CD8<sup>+</sup>T cell-mediated anti-tumor immunity. [PDF]
Liang L +8 more
europepmc +1 more source
Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim +2 more
wiley +1 more source
Regulating the regulators via targeting CD38 in the tumor microenvironment. [PDF]
Dutta N +4 more
europepmc +1 more source
Circulating exhausted CD8+ effector memory cells differentiate immune checkpoint inhibitor-induced liver injury from other acute immune-mediated liver injuries. [PDF]
Astbury S +22 more
europepmc +1 more source
The role of T cells in sepsis of distinct infectious aetiologies
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu +5 more
wiley +1 more source
A rabbit anti-human CD38 antibody for eliminating daratumumab and isatuximab interference in immunohematology testing. [PDF]
Zhang L +9 more
europepmc +1 more source
Early-Stage B-cells Predict Relapse After Rituximab Treatment in Patients With Membranous Nephropathy. [PDF]
Cheddadi Y +6 more
europepmc +1 more source
Long‐COVID or post‐acute sequelae of COVID‐19 syndrome (PASC) patients with previous severe COVID‐19 ICU history prior vaccination display sustained significant changes in their immune profile at both the cellular and the inflammatory level, revealing signatures of persistent inflammation and endothelial injury.
Louisa Ruhl +13 more
wiley +1 more source

